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Displaying results 1751 - 1760 of 8410 in total
  1. Drug

    Viltolarsen

    go.drugbank.com/drugs/DB15005
    ApprovedInvestigational

    Although corticosteroids are effective in slowing disease progression in both DMD and BMD patients, they do not address the underlying molecular pathogenesis. … [A218161, A218166, A218171, A218176, A218181, A218191, L15526] These shortened forms of dystrophin can restore partial muscle function and slow the progression of DMD.

  2. Target

    Streptogramin A acetyltransferase

    go.drugbank.com/bio_entities/BE0001238
    TargetEnterococcus faecium

    Inactivates the A compounds of streptogramin antibiotics by acetylation, thus providing resistance to these antibiotics.

    Synonyms: Vat(D)
  3. Target

    Carbonic anhydrase 5A, mitochondrial

    go.drugbank.com/bio_entities/BE0003626
    TargetEnzymeHumans

    Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3 (PubMed:24530203, PubMed:8356065, PubMed:16807956, PubMed:16686544, PubMed:17127057, PubMed:17314045, PubMed:19186056, PubMed...

    Synonyms: CA-VA, Carbonic anhydrase VA
  4. Drug

    Cod liver oil

    go.drugbank.com/drugs/DB11321
    ApprovedNutraceuticalVet approved

    Also being a rich source of vitamin A and D, cod liver oil can be taken orally as daily supplements. … It is used as an adjunct treatment and preventative therapy of rickets, osteomalacia and osteoporosis while meeting the consumption criteria.

  5. Drug

    Etryptamine

    go.drugbank.com/drugs/DB01546
    ApprovedIllicitWithdrawn

    an FDA approved antidepressant under the name Monase. … Like MDMA, increases in locomotor activity and mood elevation can be seen post administration.

  6. Drug

    Inosine pranobex

    go.drugbank.com/drugs/DB13156
    Approved

    Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.

  7. Drug

    AVR-RD-02

    go.drugbank.com/drugs/DB17650
    Investigational

    AVR-RD-02 is an investigational _ex vivo_ lentiviral gene therapy developed by AVROBIO Inc. … AVR-RD-02 is being investigated in Gaucher Disease.[L45958]

  8. Drug

    Lumiracoxib

    go.drugbank.com/drugs/DB01283
    ApprovedWithdrawn

    On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  9. Drug

    Thiabendazole

    go.drugbank.com/drugs/DB00730
    ApprovedVet approvedWithdrawn

    2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of P...

    Mixtures: DEXORYL EAR DROPS OILY SUSPENSIONCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  10. Drug

    Streptozocin

    go.drugbank.com/drugs/DB00428
    ApprovedInvestigational

    An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.

    Categories: P-glycoprotein inducers, Cytochrome P-450 CYP1A2 InducersSynonyms: N-D-Glucosyl-(2)-N'-nitrosomethylurea, N-D-Glucosyl-(2)-N'-nitrosomethylharnstoff