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Deuruxolitinib
go.drugbank.com/drugs/DB18847ApprovedInvestigational[A264108] The Janus kinase (JAK) signal transducer and activator of transcription (STAT) pathway has been implicated in the pathophysiology of alopecia areata, as it regulates the expression of inflammatory
Povidone
go.drugbank.com/drugs/DB11061ApprovedInvestigationalWithdrawnIt is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. … The clinical effectiveness of [DB06812] on wound healing remains somewhat controversial, as it was demonstrated in a few clinical studies that the application of the compound in wounds was associated with
Mixtures: Premier Value Eye Drops MtAnthrax vaccine
go.drugbank.com/drugs/DB11003ApprovedInvestigationalIt is subcutaneously or intramuscularly administered. … [L47526] It is considered one of the most likely agents to be used in a biological attack.
Phenylpropanolamine
go.drugbank.com/drugs/DB00397ApprovedVet approvedWithdrawnIt has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
Mixtures: COUGH - EN, COUGH - EN PLUSFomivirsen
go.drugbank.com/drugs/DB06759ApprovedWithdrawnIt was discovered by scientists at the National Institutes of Health (NIH) and was first developed by _Isis Pharmaceuticals_ and subsequently licensed to _Novartis_ [A31990]. … It is an antiviral agent that was used in the treatment of cytomegalovirus retinitis (CMV) in immunocompromised patients, including those with AIDS.
Brexanolone
go.drugbank.com/drugs/DB11859ApprovedInvestigationalIn particular, the use of brexanolone in treating PPD is surrounded with promise because it acts in part as a synthetic supplement for possible deficiencies in endogenous brexanolone (allopregnanolone) … Since PPD, like various other types of depression, is characterized by feelings of sadness, worthlessness or guilt, cognitive impairment, and/or possibly suicidal ideation, it is considered a life-threatening
5-methyltetrahydrofolic acid
go.drugbank.com/drugs/DB04789InvestigationalNutraceuticalIt is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases
Mixtures: Prena1 ChewCX-046684
go.drugbank.com/drugs/DB19414ApprovedIt is the active ingredient of the 2024-2025 formulation of Moderna's Spikevax vaccine.[L40074]