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Taletrectinib
go.drugbank.com/drugs/DB18711ApprovedInvestigational[L53308] Gene fusions involving _ROS1_, a proto-oncogene, have been identified as oncogenic drivers in 1-2% of patients with non-small cell lung cancer (NSCLC), in addition to other cancers at variable
Halofuginone
go.drugbank.com/drugs/DB04866InvestigationalVet approvedHalofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression.
Turoctocog alfa pegol
go.drugbank.com/drugs/DB14738ApprovedInvestigationalTuroctocog alfa pegol is a pegylated version of turoctocog alfa. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019. Fundamentally, the N8-GP moiety is identical to turoctoco...
Fendiline
go.drugbank.com/drugs/DB08980ApprovedWithdrawnIt has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective.
Nabiximols
go.drugbank.com/drugs/DB14011Investigational._ that has been purified into the active components CBD (cannabidiol) and THC (delta-9-tetrahydrocannabinol). … Although still largely debated, Cannabis has been shown to have analgesic, anticonvulsant, muscle relaxant, anxiolytic, neuroprotective, anti-oxidant, and anti-psychotic activity [A32477, A32469].
Fencamfamin
go.drugbank.com/drugs/DB01463ApprovedIllicitWithdrawnFencamfamin (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant. It is around half the potency of dexamphetamine, and is prescribed at a dose of 10-60mg, although abusers of the drug tend ...
Pyrvinium
go.drugbank.com/drugs/DB06816ApprovedInvestigationalWithdrawnSeveral forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate, triflate and pamoate. Pyrvinum's anti-cancer properties are currently under investigation.
Golnerminogene pradenovec
go.drugbank.com/drugs/DB17245InvestigationalCategories: Gene Transfer TechniquesMeglutol
go.drugbank.com/drugs/DB04377ExperimentalIt acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which
Bioymifi
go.drugbank.com/drugs/DB17493ExperimentalBioymifi is a small molecule that acts as a tumor necrosis factor-related apoptosis-induced ligand (TRAIL) mimetic.