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Methylchloroisothiazolinone
go.drugbank.com/drugs/DB14197ApprovedIt is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area. … It is found within many commercially available cosmetics, lotions, and makeup removers.
Synonyms: 5-Chloro-N-methylisothiazolin-3-oneCategories: Compounds used in a research, industrial, or household settingTenofovir disoproxil
go.drugbank.com/drugs/DB00300ApprovedInvestigationalThis drug is prescribed in combination with other drugs for the management of HIV infection as well as for Hepatitis B therapy. Tenofovir disoproxil was initially approved in 2001 [FDA label].
Categories: Antivirals used in combination for the treatment of HIV infectionsAlogliptin
go.drugbank.com/drugs/DB06203ApprovedInvestigationalChemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. … Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4).
Categories: Drugs Used in Diabetes, DPP-IV InhibitorsFomepizole
go.drugbank.com/drugs/DB01213ApprovedVet approvedFomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. … Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Categories: Compounds used in a research, industrial, or household settingLamivudine
go.drugbank.com/drugs/DB00709ApprovedInvestigationalA reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. … It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
International brands: LamivirMixtures: N/A, N/AAcetylcarnitine
go.drugbank.com/drugs/DB08842ApprovedInvestigationalAcetylcarnitine can be synthesized, but it is also naturally found in adequate amounts in healthy humans. … Acetylcarnitine is an investigational drug in the United states, Italy, United Kingdom, China, Israel, and Norway, and it is approved in Italy, Portugal, Argentina, Chile, Philippines, Australia, and India
International brands: Memorx IQ PlusNateglinide
go.drugbank.com/drugs/DB00731ApprovedNateglinide is extensively metabolized in the liver and excreted in urine (83%) and feces (10%). The major metabolites possess less activity than the parent compound. … Meglitnides may have a neutral effect on weight or cause a slight increase in weight.
Categories: Drugs Used in DiabetesBioallethrin
go.drugbank.com/drugs/DB13746ApprovedWithdrawnA mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin. … Bioallethrin refers to a mixture of two of the allethrin isomers (1R,trans;1R and 1R,trans;1S) in an approximate ratio of 1:1, where both isomers are active ingredients.
Categories: Compounds used in a research, industrial, or household settingPeginesatide
go.drugbank.com/drugs/DB08894ApprovedWithdrawnChemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself. … Peginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life.
Categories: Compounds used in a research, industrial, or household settingTenapanor
go.drugbank.com/drugs/DB11761ApprovedInvestigational[L8558] It was first designed and synthesized in 2012. … a novel alternative in the treatment of IBS-C.