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Displaying results 1771 - 1780 of 10000 in total
  1. Drug

    Fingolimod

    go.drugbank.com/drugs/DB08868
    ApprovedInvestigational

    Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. … [A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis.

    Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesProducts: LEBRINA® 0.5 MG, VINTOR 0.5 MG KAPSÜL, 7 ADET
  2. Drug

    Rofecoxib

    go.drugbank.com/drugs/DB00533
    ApprovedWithdrawn

    Rofecoxib has a half-life of 17 hours and its mean oral bioavailability at therapeutically recommended doses of 125, 25, and 50 mg is approximately 93%. … Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety.

    Categories: COX-2 Inhibitors, Cytochrome P-450 SubstratesSynonyms: 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone, 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone
  3. Drug

    Pentoxyverine

    go.drugbank.com/drugs/DB11186
    ApprovedWithdrawn

    Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant [A32717], and local anesthetic properties. … Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate.

    Mixtures: Pancold A, GAYABEN 150 ML SURUPProducts: PENTOXYVERIN AL 1.35 MG/ML, PENTOXYVERIN AL 19MG/ML
  4. Drug

    Rebamipide

    go.drugbank.com/drugs/DB11656
    ApprovedInvestigational

    Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingProducts: MUCOSTA TABLETS 100 MG, บาปิด 100
  5. Drug

    Desogestrel

    go.drugbank.com/drugs/DB00304
    ApprovedInvestigational

    Desogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. … [A176339] It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological activity.

    Mixtures: Desofemine 20 Mikrogramm/150 Mikrogramm Filmtabletten, Desogestrel/Ethinylestradiol Effik 150 Mikrogramm/20 Mikrogramm TablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  6. Drug

    Phleum pratense pollen

    go.drugbank.com/drugs/DB10394
    ApprovedInvestigational

    Phleum pratense pollen allergenic extract is used in allergenic testing.

    Mixtures: SLITone ULTRA D. glomerata/ L. perenne/ P. pratense/ P. pratensis/ A. odoratum, Oralair 100 IRProducts: GRAZAX 75.000 SQ-T ORAL LIYOFILIZAT 100 TABLET, Standardized Grass Pollen - Timothy (100 Bau/ml)
  7. Drug

    Bismuth subsalicylate

    go.drugbank.com/drugs/DB01294
    ApprovedVet approved

    [L32318] Bismuth subsalicylate is a component of HELIDAC Therapy (bismuth subsalicylate, [metronidazole], and [tetracycline]), which is a treatment regimen indicated for the eradication of _H. pylori_ … [A230733] Bismuth subsalicylate has been around for over 100 years: it was originally developed in 1901 for hygienic use and sanitation for cholera infection.

    Synonyms: 2-Hydroxy-benzo[1,3,2]dioxabismin-4-oneProducts: BİZMOPEPTOL MAX 1050 MG/30 ML ORAL SÜSPANSİYON, 240 ML, BİZMOPEPTOL 525 MG/30 ML ORAL SÜSPANSİYON , 240 ML
  8. Drug

    Diphenoxylate

    go.drugbank.com/drugs/DB01081
    ApprovedIllicitInvestigational

    When diphenoxylate is used alone, it is classified as a Schedule II. … A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine.

    Synonyms: Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylate, 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl esterMixtures: PHARMANIAGA DIPHENOXYLATE A TABLET, LOMOTİL 2,5 MG + 0,025 MG / 5 ML ORAL ÇÖZELTİ, 60 ML
  9. Drug

    Norethisterone

    go.drugbank.com/drugs/DB00717
    ApprovedInvestigational

    [A10367] Norethisterone mimics the actions of endogenous [progesterone], albeit with a greater potency,[A188075] and is used on its own or in combination with estrogen derivatives in a variety of applications … Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins.

    Synonyms: 17-hydroxy-19-nor-17-α-pregn-4-en-20-yn-3-one, 17-β-hydroxy-19-norpregn-4-en-20-yn-3-oneInternational brands: Primolut-N
  10. Drug

    Calcium ascorbate

    go.drugbank.com/drugs/DB14483
    ApprovedNutraceutical

    Mixtures: Ester-C 500 mg, Ester-C 500 mgCategories: Compounds used in a research, industrial, or household setting, Vitamin C and analogues