Phleum pratense pollen
Explore a selection of our essential drug information below, or:
Identification
- Summary
Phleum pratense pollen is an extract from Phleum pratense pollen used in allergy testing.
- Brand Names
- Grastek, Oralair 100, Oralair 300, Oralair Children and Adolescents Sample Kit
- Generic Name
- Phleum pratense pollen
- DrugBank Accession Number
- DB10394
- Background
Phleum pratense pollen allergenic extract is used in allergenic testing.
- Type
- Biotech
- Groups
- Approved, Investigational
- Biologic Classification
- Allergenics
Allergen Extract - Synonyms
- Allergenic extract, grass, timothy
- Allergenic extract, timothy grass
- Allergenic extract,timothy grass pollen
- Common timothy pollen
- Grass pollen extract
- Phleum nodosum pollen
- Phleum pratense
- Phleum pratense pollen extract
- Standardized timothy grass pollen
- Timothy grass (phleum pretense) pollen standardized
- Timothy grass pollen
- Timothy grass pollen extract
- Timothy grass pollen extracts
- Timothy pollen
Pharmacology
- Indication
Phleum pratense pollen is an allergen extract included in an allergenic testing product called ORALAIR. It is indicated as immunotherapy for the treatment of grass pollen-induced allergic rhinitis with or without conjunctivitis confirmed by positive skin test or in vitro testing for pollen38 specific IgE antibodies for any of the five grass species contained in this product. ORALAIR is approved for use in persons 5 through 65 years of age.3
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination for diagnostic process Allergic rhinitis due to pollen •••••••••••• Used in combination for diagnostic process Allergic rhinitis due to pollen •••••••••••• •••••••••••••• - Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcebutolol The risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Acebutolol. Atenolol The risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Atenolol. Benazepril The risk or severity of adverse effects can be increased when Benazepril is combined with Phleum pratense pollen. Betaxolol The risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Betaxolol. Bisoprolol The risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Bisoprolol. - Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Active Moieties
Name Kind UNII CAS InChI Key Phleum pratense top unknown S7PW24BX20 Not Available Not applicable - Brand Name Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Allergen Pack Timothy Grass Solution 10000 [BAU]/1mL Intradermal; Subcutaneous Alvix Laboratories 2015-07-09 2018-03-08 US Allergenic Extract - Standardized Grass Pollen - Timothy Liquid 100000 unit / mL Intradermal; Subcutaneous Greer Laboratories, Inc. 2000-10-30 Not applicable Canada Allergenic Extract - Standardized Grass Pollen - Timothy Liquid 10000 unit / mL Intradermal; Subcutaneous Greer Laboratories, Inc. 2015-03-10 Not applicable Canada Allergenic Extract - Standardized Timothy Grass Pollen Liquid 100000 unit / mL Intradermal; Percutaneous; Subcutaneous ALK-Abello, Inc. 2009-07-30 Not applicable Canada Center-AL - Phleum Pratense Pollen Injection, suspension 10000 [PNU]/1mL Subcutaneous ALK-Abello, Inc. 1975-01-15 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image 5 Grass Mix Phleum pratense pollen (1000 [PNU]/1mL) + Agrostis gigantea pollen (1000 [PNU]/1mL) + Anthoxanthum odoratum pollen (1000 [PNU]/1mL) + Dactylis glomerata pollen (1000 [PNU]/1mL) + Poa pratensis pollen (1000 [PNU]/1mL) Injection, solution Subcutaneous ALK-Abello, Inc. 1975-01-15 2023-05-25 US 5 Grass Mix Phleum pratense pollen (20000 [PNU]/1mL) + Agrostis gigantea pollen (20000 [PNU]/1mL) + Anthoxanthum odoratum (20000 [PNU]/1mL) + Dactylis glomerata pollen (20000 [PNU]/1mL) + Poa pratensis pollen (20000 [PNU]/1mL) Injection, solution Subcutaneous ALK-Abello, Inc. 1975-01-15 2023-05-25 US 5 Grass Mix Phleum pratense pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Anthoxanthum odoratum pollen (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Poa pratensis pollen (10000 [PNU]/1mL) Injection, solution Subcutaneous ALK-Abello, Inc. 1975-01-15 2023-05-25 US 5 Grass Mix Phleum pratense pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Anthoxanthum odoratum (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Poa pratensis pollen (10000 [PNU]/1mL) Injection, solution Subcutaneous ALK-Abello, Inc. 1975-01-15 Not applicable US 5 Grass Mix Phleum pratense pollen (5000 [PNU]/1mL) + Agrostis gigantea pollen (5000 [PNU]/1mL) + Anthoxanthum odoratum pollen (5000 [PNU]/1mL) + Dactylis glomerata pollen (5000 [PNU]/1mL) + Poa pratensis pollen (5000 [PNU]/1mL) Injection, solution Subcutaneous ALK-Abello, Inc. 1975-01-15 2023-05-25 US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Allergen Pack Timothy Grass Phleum pratense pollen (10000 [BAU]/1mL) Solution Intradermal; Subcutaneous Alvix Laboratories 2015-07-09 2018-03-08 US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 0P46LFE4VC
- CAS number
- Not Available
References
- General References
- TePas EC, Hoyte EG, McIntire JJ, Umetsu DT: Clinical efficacy of microencapsulated timothy grass pollen extract in grass-allergic individuals. Ann Allergy Asthma Immunol. 2004 Jan;92(1):25-31. [Article]
- Patel P, Salapatek AM: Pollinex Quattro: a novel and well-tolerated, ultra short-course allergy vaccine. Expert Rev Vaccines. 2006 Oct;5(5):617-29. [Article]
- FDA Approved Drug Products: ORALAIR 6 (Sweet Vernal, Orchard, Perennial Rye, Timothy, and Kentucky Blue Grass Mixed Pollens Allergen Extract) Tablet for Sublingual Use [Link]
- External Links
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample dataNot Available Completed Not Available Allergic Reaction 1 somestatus stop reason just information to hide 4 Completed Treatment Allergic Reaction 1 somestatus stop reason just information to hide 4 Completed Treatment Rhinoconjunctivitis, Allergic 1 somestatus stop reason just information to hide 4 Completed Treatment Seasonal Allergic Rhinitis 1 somestatus stop reason just information to hide 3 Completed Treatment Allergic Reaction 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, solution Subcutaneous Solution Intradermal; Subcutaneous 10000 [BAU]/1mL Liquid Intradermal; Percutaneous; Subcutaneous Liquid Intradermal; Subcutaneous 10000 unit / mL Liquid Intradermal; Subcutaneous 100000 unit / mL Liquid Intradermal; Percutaneous; Subcutaneous 100000 unit / mL Liquid Subcutaneous Solution Intradermal; Subcutaneous Injection, suspension Subcutaneous 10000 [PNU]/1mL Injection, suspension Subcutaneous 20000 [PNU]/1mL Injection, solution Percutaneous Tablet Sublingual 2800 [BAU]/1 Tablet, orally disintegrating Sublingual 2800 unit Tablet Oral 75000 SQ-T Powder Oral 75000 SQ-T Tablet Oral Kit Sublingual Kit; tablet, orally disintegrating Sublingual Tablet Sublingual 100 [IR] Tablet Sublingual 300 [IR] Tablet, orally disintegrating Sublingual Tablet Sublingual Liquid Intradermal 100 unit / mL Liquid Intradermal 1000 unit / mL Solution Percutaneous; Subcutaneous 10000 unit / mL Solution Percutaneous; Subcutaneous 100000 unit / mL Injection, solution Intradermal Injection, solution Percutaneous; Subcutaneous Injection, solution Intradermal 100 [BAU]/1mL Injection, solution Intradermal 1000 [BAU]/1mL Injection, solution Percutaneous; Subcutaneous 10000 [BAU]/1mL Injection Cutaneous; Intradermal; Subcutaneous 100000 [BAU]/1mL Injection, solution Intradermal; Subcutaneous 10000 [BAU]/1mL Injection, solution Intradermal; Subcutaneous 100000 [BAU]/1mL Injection, solution Percutaneous; Subcutaneous 100000 [BAU]/1mL Solution Intradermal; Percutaneous; Subcutaneous 10000 [BAU]/1mL Solution Intradermal; Percutaneous; Subcutaneous 100000 [BAU]/1mL Solution Intradermal; Percutaneous; Subcutaneous Injection, solution Subcutaneous 10000 [BAU]/1mL Injection, solution Subcutaneous 100000 [BAU]/1mL Solution Percutaneous 10000 [BAU]/1mL Solution Percutaneous 100000 [BAU]/1mL Injection, solution Intradermal; Subcutaneous - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at December 01, 2015 20:03 / Updated at October 29, 2024 14:47