Phleum pratense pollen

Identification

Summary

Phleum pratense pollen is an extract from Phleum pratense pollen used in allergy testing.

Brand Names
Grastek, Oralair 100, Oralair 300, Oralair Children and Adolescents Sample Kit
Generic Name
Phleum pratense pollen
DrugBank Accession Number
DB10394
Background

Phleum pratense pollen allergenic extract is used in allergenic testing.

Type
Biotech
Groups
Approved, Investigational
Biologic Classification
Allergenics
Allergen Extract
Synonyms
  • Allergenic extract, grass, timothy
  • Allergenic extract, timothy grass
  • Allergenic extract,timothy grass pollen
  • Common timothy pollen
  • Grass pollen extract
  • Phleum nodosum pollen
  • Phleum pratense
  • Phleum pratense pollen extract
  • Standardized timothy grass pollen
  • Timothy grass (phleum pretense) pollen standardized
  • Timothy grass pollen
  • Timothy grass pollen extract
  • Timothy grass pollen extracts
  • Timothy pollen

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AcebutololThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Acebutolol.
AtenololThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Atenolol.
BenazeprilThe risk or severity of adverse effects can be increased when Benazepril is combined with Phleum pratense pollen.
BetaxololThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Betaxolol.
BisoprololThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Bisoprolol.
CaptoprilThe risk or severity of adverse effects can be increased when Captopril is combined with Phleum pratense pollen.
CarvedilolThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Carvedilol.
CeliprololThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Celiprolol.
CilazaprilThe risk or severity of adverse effects can be increased when Cilazapril is combined with Phleum pratense pollen.
EnalaprilThe risk or severity of adverse effects can be increased when Enalapril is combined with Phleum pratense pollen.
Interactions
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Food Interactions
Not Available

Products

Products
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Active Moieties
NameKindUNIICASInChI Key
Phleum pratense topunknownS7PW24BX20Not AvailableNot applicable
Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Allergen Pack Timothy GrassSolution10000 [BAU]/1mLIntradermal; SubcutaneousAlvix Laboratories2015-07-092018-03-08US flag
Allergenic Extract - Standardized Grass Pollen - TimothyLiquid10000 unit / mLIntradermal; SubcutaneousGreer Laboratories2015-03-10Not applicableCanada flag
Allergenic Extract - Standardized Grass Pollen - TimothyLiquid100000 unit / mLIntradermal; SubcutaneousGreer Laboratories2000-10-30Not applicableCanada flag
Allergenic Extract - Standardized Timothy Grass PollenLiquid100000 unit / mLIntradermal; Percutaneous; SubcutaneousAlk Abello, Inc.2009-07-30Not applicableCanada flag
Center-AL - Phleum Pratense PollenInjection, suspension10000 [PNU]/1mLSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
Center-AL - Phleum Pratense PollenInjection, suspension20000 [PNU]/1mLSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
GrastekTablet2800 [BAU]/1SublingualMerck Sharp & Dohme Corp.2014-04-112017-08-18US flag
GrastekTablet2800 [BAU]/1SublingualALK-Abello A S2014-04-11Not applicableUS flag
GrastekTablet, orally disintegrating2800 unitSublingualAlk Abello A/S2014-01-14Not applicableCanada flag
OralairTablet300 [IR]SublingualStallergenes Canada Inc2012-07-26Not applicableCanada flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
5 Grass MixPhleum pratense pollen (20000 [PNU]/1mL) + Agrostis gigantea pollen (20000 [PNU]/1mL) + Anthoxanthum odoratum (20000 [PNU]/1mL) + Dactylis glomerata pollen (20000 [PNU]/1mL) + Poa pratensis pollen (20000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixPhleum pratense pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Anthoxanthum odoratum pollen (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Poa pratensis pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixPhleum pratense pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Anthoxanthum odoratum (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Poa pratensis pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixPhleum pratense pollen (5000 [PNU]/1mL) + Agrostis gigantea pollen (5000 [PNU]/1mL) + Anthoxanthum odoratum pollen (5000 [PNU]/1mL) + Dactylis glomerata pollen (5000 [PNU]/1mL) + Poa pratensis pollen (5000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixPhleum pratense pollen (100 [PNU]/1mL) + Agrostis gigantea pollen (100 [PNU]/1mL) + Anthoxanthum odoratum pollen (100 [PNU]/1mL) + Dactylis glomerata pollen (100 [PNU]/1mL) + Poa pratensis pollen (100 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixPhleum pratense pollen (1000 [PNU]/1mL) + Agrostis gigantea pollen (1000 [PNU]/1mL) + Anthoxanthum odoratum pollen (1000 [PNU]/1mL) + Dactylis glomerata pollen (1000 [PNU]/1mL) + Poa pratensis pollen (1000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
6 Grass MixPhleum pratense pollen (20000 [PNU]/1mL) + Agrostis gigantea pollen (20000 [PNU]/1mL) + Dactylis glomerata pollen (20000 [PNU]/1mL) + Festuca pratensis pollen (20000 [PNU]/1mL) + Lolium perenne pollen (20000 [PNU]/1mL) + Poa pratensis pollen (20000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
6 Grass MixPhleum pratense pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Festuca pratensis pollen (10000 [PNU]/1mL) + Lolium perenne pollen (10000 [PNU]/1mL) + Poa pratensis pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
7 Grass MixPhleum pratense pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Anthoxanthum odoratum (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Festuca pratensis pollen (10000 [PNU]/1mL) + Lolium perenne pollen (10000 [PNU]/1mL) + Poa pratensis pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
7 Grass MixPhleum pratense pollen (20000 [PNU]/1mL) + Agrostis gigantea pollen (20000 [PNU]/1mL) + Anthoxanthum odoratum (20000 [PNU]/1mL) + Dactylis glomerata pollen (20000 [PNU]/1mL) + Festuca pratensis pollen (20000 [PNU]/1mL) + Lolium perenne pollen (20000 [PNU]/1mL) + Poa pratensis pollen (20000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Allergen Pack Timothy GrassPhleum pratense pollen (10000 [BAU]/1mL)SolutionIntradermal; SubcutaneousAlvix Laboratories2015-07-092018-03-08US flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
65M88RW2EG
CAS number
Not Available

References

General References
  1. TePas EC, Hoyte EG, McIntire JJ, Umetsu DT: Clinical efficacy of microencapsulated timothy grass pollen extract in grass-allergic individuals. Ann Allergy Asthma Immunol. 2004 Jan;92(1):25-31. [Article]
  2. Patel P, Salapatek AM: Pollinex Quattro: a novel and well-tolerated, ultra short-course allergy vaccine. Expert Rev Vaccines. 2006 Oct;5(5):617-29. [Article]
PubChem Substance
347910569
RxNav
851994

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedTreatmentRhinoconjunctivitis, Allergic1
4CompletedTreatmentSeasonal Allergic Rhinitis1
3CompletedTreatmentSeasonal Allergic Rhinitis1
3RecruitingTreatmentHypersensitivity1
Not AvailableCompletedNot AvailableHypersensitivity1
Not AvailableSuspendedBasic ScienceImmunologic Desensitization1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solutionSubcutaneous
SolutionIntradermal; Subcutaneous10000 [BAU]/1mL
LiquidIntradermal; Percutaneous; Subcutaneous
LiquidIntradermal; Subcutaneous10000 unit / mL
LiquidIntradermal; Subcutaneous100000 unit / mL
LiquidIntradermal; Percutaneous; Subcutaneous100000 unit / mL
LiquidSubcutaneous
SolutionIntradermal; Subcutaneous
Injection, suspensionSubcutaneous10000 [PNU]/1mL
Injection, suspensionSubcutaneous20000 [PNU]/1mL
Injection, solutionPercutaneous
TabletSublingual2800 [BAU]/1
Tablet, orally disintegratingSublingual2800 unit
TabletOral
PowderOral
KitSublingual
TabletSublingual100 [IR]
TabletSublingual300 [IR]
Tablet, orally disintegratingSublingual
TabletSublingual
LiquidIntradermal100 unit / mL
LiquidIntradermal1000 unit / mL
SolutionPercutaneous; Subcutaneous10000 unit / mL
SolutionPercutaneous; Subcutaneous100000 unit / mL
Injection, solutionIntradermal
Injection, solutionPercutaneous; Subcutaneous
Injection, solutionIntradermal100 [BAU]/1mL
Injection, solutionIntradermal1000 [BAU]/1mL
Injection, solutionPercutaneous; Subcutaneous10000 [BAU]/1mL
InjectionCutaneous; Intradermal; Subcutaneous100000 [BAU]/1mL
Injection, solutionIntradermal; Subcutaneous10000 [BAU]/1mL
Injection, solutionIntradermal; Subcutaneous100000 [BAU]/1mL
Injection, solutionPercutaneous; Subcutaneous100000 [BAU]/1mL
SolutionIntradermal; Percutaneous; Subcutaneous10000 [BAU]/1mL
SolutionIntradermal; Percutaneous; Subcutaneous100000 [BAU]/1mL
SolutionIntradermal; Percutaneous; Subcutaneous
Injection, solutionSubcutaneous10000 [BAU]/1mL
Injection, solutionSubcutaneous100000 [BAU]/1mL
SolutionPercutaneous10000 [BAU]/1mL
SolutionPercutaneous100000 [BAU]/1mL
Injection, solutionIntradermal; Subcutaneous
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on December 01, 2015 20:03 / Updated on July 24, 2021 14:58