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Foreskin keratinocyte (neonatal)
go.drugbank.com/drugs/DB10772ApprovedThe defining moment in skin culture was in 1975 when Rheinwald and Green successfully grew human keratinocytes on lethally irradiated murine fibroblasts. … Foreskin keratinocytes are an important ingredient in several skin substitutes [L2460], used for various indications.
Lipoic acid
go.drugbank.com/drugs/DB00166ApprovedInvestigationalNutraceuticalA vitamin-like antioxidant.
Categories: Compounds used in a research, industrial, or household settingRosin
go.drugbank.com/drugs/DB11165ApprovedIn the pharmaceuticals, rosin is used in film forming and coating tablets and enterically administered agents, as well as forming microcapsules and nanoparticles. … Rosin has shown to mediate antibacterial actions on Gram-positive bacterial species [A27267].
Categories: Compounds used in a research, industrial, or household settingMaftivimab
go.drugbank.com/drugs/DB15899ApprovedInvestigationalEbola virus (EBOV) remains an important human pathogen within the _Ebolavirus_ genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. … INMAZEB™ is produced by Regeneron Pharmaceuticals and was granted FDA approval on October 14, 2020.[L17320]
Paliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalIt is available as an extended-release tablet, a once-monthly intramuscular injection, an every-three-month intramuscular injection, and a twice-yearly gluteal injection.[L16168,L37744,L4137,L37749] … Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006.
Products: Palibon 25 mg Depot-Injektionssuspension in einer Fertigspritze, Palibon 50 mg Depot-Injektionssuspension in einer FertigspritzeFenfluramine
go.drugbank.com/drugs/DB00574ApprovedIllicitInvestigationalWithdrawnfrom the market in 1997. … [A214694, A214709, A214712, A214715] Fenfluramine is a serotonergic phenethylamine originally used as an appetite suppressant until concerns regarding cardiotoxicity in obese patients lead to its withdrawal
Temsirolimus
go.drugbank.com/drugs/DB06287ApprovedInvestigationalTemsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007. … Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel.
Midazolam
go.drugbank.com/drugs/DB00683ApprovedIllicitInvestigational[L45098] In late 2018, the intramuscular preparation was approved by the FDA for the treatment of status epilepticus in adults. … [L45098] In May 2019, the nasal spray of midazolam was approved for the acute treatment of distinctive intermittent, stereotypic seizure episodes in patients 12 years of age and older.
Products: N/a, Midazolam in Sodium ChlorideLoxoprofen
go.drugbank.com/drugs/DB09212ApprovedInvestigationalA transdermal preparation was approved for use in Japan in January 2006. … It is marketed under the trade name Loxonin in Brazil, Mexico and Japan by Sankyo, as Loxomac in India, and as Oxeno in Argentina.
Oxytocin
go.drugbank.com/drugs/DB00107ApprovedInvestigationalVet approved[A229008] It plays an important role in pair bonding, social cognition and functioning, and even fear conditioning. … [A229108] Oxytocin continues to be an important tool in modern obstetrics to induce labor when indicated and to manage postpartum hemorrhage.