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Fenoprofen
go.drugbank.com/drugs/DB00573ApprovedIt is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Categories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-NarcoticTyrothricin
go.drugbank.com/drugs/DB13503ApprovedWithdrawnNevertheless, as tyrothricin is both cytolytic and hemolytic, it does demonstrate systemic toxicity [L4019, L4021, L4022], although certain formulations that are safe for human use like throat lozenges … Moreover, tyrothricin possesses broad spectrum Gram-positive antibacterial and antifungal activity that has not seen many - if any - significant reportings of microbial resistance during the over 60 years
Mixtures: Emercreme No4 Ont EfaZiconotide
go.drugbank.com/drugs/DB06283ApprovedInvestigational[A202829, A202835, A202838, A202841, A202850, A202859, L13389] Ziconotide was granted FDA approval on December 28, 2004 for marketing by TerSera therapeutics LLC. under the name Prialt. … [L13389] To date, ziconotide is the only calcium channel blocking peptide approved for use by the FDA.[A202835]
Categories: Analgesics, Non-Narcotic, Calcium Channels, N-TypeSipuleucel-T
go.drugbank.com/drugs/DB06688ApprovedInvestigationalThe treatment initially cost $93,000 at the time of FDA approval, but rose to over $100,000 in 2014. … In metastatic prostate cancer, it has extended survival by median 4.1 months (IMPACT Phase III trial data). Sipuleucel-T is marketed under the brand name Provenge by Dendreon Corporation.
Sutimlimab
go.drugbank.com/drugs/DB14996ApprovedInvestigational[L40114,A245144] Sutimlimab was also approved by the European Commission in November 2022.[L44116] … [A245144] Hemolysis in patients with CAD is driven by complement activation, which initiates a cascade that ultimately leads to both intra- and extravascular hemolysis.
Telithromycin
go.drugbank.com/drugs/DB00976ApprovedSimilar to the macrolide antibiotics, telithromycin prevents bacterial growth by interfering with bacterial protein synthesis. … Telithromycin, a semi-synthetic erythromycin derivative, belongs to a new chemical class of antibiotics called ketolides.
Dipotassium phosphate
go.drugbank.com/drugs/DB09414ApprovedInvestigationalDipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Nystatin
go.drugbank.com/drugs/DB00646ApprovedInvestigationalVet approved[L10686] It is one of the most effective antifungal agents synthesized by bacteria, in this case a strain of _Streptomyces noursei_,[L10776] and is closely related to [amphotericin B], differing only slightly … [A188562] Nystatin has a greater antifungal activity than amphotericin B - parenterally administered nystatin, however, is associated with significant toxicity and is not available in a formulation appropriate
Mixtures: PERFESSIL NF, BABYSKIN® N CREMAInternational brands: Diaper NZVarenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalFood and Drug Administration warned that Varenicline, in the form of Pfizer Inc's quit-smoking drug, Chantix, has been associated with seizures and that some patients who drink while taking the drug may
Enlicitide
go.drugbank.com/drugs/DB22580ApprovedInvestigational[L63795] Adverse reaction frequencies were similar to placebo and the drug carries no contraindications. … (CORALreef Lipids), and by 59% in patients with HeFH (CORALreef HeFH), with comparable reductions in non-HDL-C and apolipoprotein B.