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Displaying results 1781 - 1790 of 3388 in total
  1. Drug

    Lomerizine

    go.drugbank.com/drugs/DB14065
    Experimental

    Lomerizine is a diphenylmethylpiperazine calcium channel blocker with relatively selective central nervous system (CNS) effects. This drug is used to prophylactically treat migraines and is also being investigated against eye-related dis...

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  2. Drug

    Dexniguldipine

    go.drugbank.com/drugs/DB14068
    Experimental

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  3. Drug

    ONT-093

    go.drugbank.com/drugs/DB14069
    Experimental

    ONT-093 is an orally bioavailable inhibitor of P-glycoprotein (P-gp). … In pre-clinical studies, ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics.

    Categories: P-glycoprotein inhibitors
  4. Drug

    Macelignan

    go.drugbank.com/drugs/DB14129
    Investigational

    Macelignan is an NSAID with antioxidant, free radical scavenging, and neuroprotective activities.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inhibitors
  5. Drug

    8-chlorotheophylline

    go.drugbank.com/drugs/DB14132
    Experimental

    Because adenosine causes a decrease in neuronal firing, blockade of the adenosine receptor causes the reverse effect resulting in excitation. … system. 8-chlorotheophylline produces a number of effects including nervousness, restlessness, insomnia, headache, and nausea, which are primarily attributed to its ability to block the adenosine receptor

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  6. Drug

    Beroctocog alfa

    go.drugbank.com/drugs/DB14473
    ApprovedInvestigational

    Mixtures: HAEMATE PProducts: Humate-P
  7. Drug

    Hydrocortisone acetate

    go.drugbank.com/drugs/DB14539
    ApprovedInvestigationalVet approved

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inducers
  8. Drug

    Hydrocortisone cypionate

    go.drugbank.com/drugs/DB14541
    ApprovedVet approvedWithdrawn

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inducers
  9. Drug

    Hydrocortisone valerate

    go.drugbank.com/drugs/DB14544
    ApprovedVet approved

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inducers
  10. Drug

    Sophora flavescens root

    go.drugbank.com/drugs/DB14565
    Investigational

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors