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Displaying results 171 - 180 of 16416 in total
  1. Drug

    Descarboxy-nor-N(Omega)-Hydroxy-L-Arginine

    go.drugbank.com/drugs/DB04197
    Experimental

    Synonyms: Descarboxy-nor-N(Omega)-Hydroxy-L-Arginine
  2. Drug

    Relmacabtagene autoleucel

    go.drugbank.com/drugs/DB18979
    Investigational

    Synonyms: AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) TRANSDUCED WITH A NONREPLICATIVE SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR ENCODING A CHIMERIC ANTIGEN RECEPTOR
  3. Drug

    Evorpacept

    go.drugbank.com/drugs/DB17573
    Investigational

    Evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: A CD47-binding, fusion protein containing a high affinity engineered D1 domain of human signal regulatory protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domain
  4. Drug

    Verpasep caltespen

    go.drugbank.com/drugs/DB04959
    Investigational

    E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes. … Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a number of different cancers.

    Synonyms: Recombinant fusion protein of Mycobacterium bovis BCG Hsp65 and HPV16 E7
  5. Drug

    Tefidsogene civaparvovec

    go.drugbank.com/drugs/DB16789
    Investigational

    It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes … Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing.

    Synonyms: EXONS 2-9 FROM HIDS AND A SPLICE ACCEPTOR SITE (SA), A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS
  6. Drug

    Vanglusagene ensiparvovec

    go.drugbank.com/drugs/DB17675
    Investigational

    Synonyms: recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) and a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase
  7. Drug

    Orvacabtagene autoleucel

    go.drugbank.com/drugs/DB17231
    Investigational

    Synonyms: CD4+ CD8+ T CELLS ARE DERIVED FROM ISOLATED BLOOD OF THE PATIENT AND ARE TRANSDUCED WITH NON-REPLICATIVE SELF-INACTIVATING (SIN) LENTIVIRAL V, JCARH125 CONSISTS OF HUMAN CULTURE EXPANDED GENETICALLY MODIFIED AUTOLOGOUS T CELLS FOR CELL-BASED GENE THERAPY.
  8. Drug

    Nicotine

    go.drugbank.com/drugs/DB00184
    ApprovedInvestigational

    It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission.

    Mixtures: Nicorette and Aquafresh Fruit Chill and Extreme Clean WhiteningCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inducers
  9. Drug

    Phenylacetic acid

    go.drugbank.com/drugs/DB09269
    Approved

    Phenylacetic acid is an organic compound containing a phenyl functional group and a carboxylic acid functional group. It is a white solid with a disagreeable odor. … Because it is used in the illicit production of phenylacetone (used in the manufacture of substituted amphetamines), it is subject to controls in countries including the United States and China.

    Mixtures: Sodium Phenylacetate and Sodium Benzoate, Sodium Phenylacetate and Sodium BenzoateCategories: Acids, Carbocyclic, Carboxylic Acids
  10. Drug

    Royal jelly

    go.drugbank.com/drugs/DB14250
    Investigational

    Royal jelly is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: Shine Oramin Natural Korean Ginseng + Royal Jelly with Multivitamins and Minerals., Vitasen C 100 with Royal Jelly Chewable TabletSynonyms: Honey Bee Secretion Used in the Nutrition of Larvae and Adult Queens Secreted From Worker Bee Hypopharyngeal Glands