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Displaying results 171 - 180 of 151858 in total
  1. Drug

    Quizartinib

    go.drugbank.com/drugs/DB12874
    ApprovedInvestigational

    Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated … [A260641] Additionally, quizartinib also demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although with a 10-fold lower affinity compared to wild-type FLT3.

    Synonyms: N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol-2-yl)phenyl)ureaCategories: Antineoplastic and Immunomodulating Agents, Heterocyclic Compounds, 1-Ring
  2. Drug

    Camphor

    go.drugbank.com/drugs/DB01744
    ApprovedInvestigationalWithdrawn

    The FDA ruled that camphorated oil could not be marketed in the United States and that no product could contain a concentration higher than 11%. … When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity.

    Mixtures: Neo Medicated Plaster with Ginger and Lemongrass Oil Aroma, LUKE`S OILCategories: Basic Lotions and Liniments, Antipruritics and Local Anesthetics
  3. Drug

    Drotrecogin alfa

    go.drugbank.com/drugs/DB00055
    ApprovedWithdrawn

    It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. … Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology.

    Categories: Recombinant Activated Protein C, Enzymes and CoenzymesSynonyms: Activated protein C, Recombinant human activated protein C (rH-APC)
  4. Drug

    Hydroxyurea

    go.drugbank.com/drugs/DB01005
    ApprovedInvestigational

    need for therapeutic monitoring, and serious side effects of secondary cancer and birth defects. … Hydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928.

    Categories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 CYP2D6 InhibitorsSynonyms: Hydroxy Urea, N-Hydroxyurea
  5. Drug

    Amidapsone

    go.drugbank.com/drugs/DB20346
    Experimental

    Amidapsone is a small molecule drug. Amidapsone has a monoisotopic molecular weight of 291.07 Da.

    Synonyms: (p-sulfanilylphenyl)urea
  6. Drug

    1-(2-Amidinophenyl)-3-(Phenoxyphenyl)Urea

    go.drugbank.com/drugs/DB03337
    Experimental

    Synonyms: 1-(2-Amidinophenyl)-3-(Phenoxyphenyl)Urea
  7. Drug

    Rosa centifolia flower oil

    go.drugbank.com/drugs/DB14363
    Investigational

    Rosa centifolia flower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Cabbage Rose Oil, Rosa centifolia flower oil
  8. Drug

    Crypthecodinium cohnii DHA oil

    go.drugbank.com/drugs/DB11099
    Investigational

    Mixtures: L-Methyl PNV DHASynonyms: Crypthecodinium cohnii DHA oil
  9. Drug

    CHF5633

    go.drugbank.com/drugs/DB18696
    Investigational

    CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a … synthetic SP-B analogue.

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue
  10. Drug

    Ginkgo biloba leaf oil

    go.drugbank.com/drugs/DB14285
    Investigational

    Ginkgo biloba leaf oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Common Ginkgo Leaf Oil, Ginkgo biloba leaf oil