Search

Displaying results 171 - 180 of 5419 in total
  1. Drug

    Gemtuzumab ozogamicin

    go.drugbank.com/drugs/DB00056
    ApprovedInvestigational

    However, it was voluntarily withdrawn from the market in 2010 due to safety concerns, increased patient deaths and insufficient evidence of clinical benefit during confirmatory trials [L941].

    Products: MYLOTARG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 5MG/VIAL
  2. Drug

    Oxaliplatin

    go.drugbank.com/drugs/DB00526
    ApprovedInvestigational

    [A797] Due to this chemical moiety, oxaliplatin readily undergoes non-enzymatic biotransformation, thus complicating oxaliplatin's pharmacokinetics. … [A260396] However, due to the structure of oxaliplatin, its adducts make the binding of mismatch repair protein to DNA harder compared to cisplatin or carboplatin's adducts, resulting in greater cytotoxic

    Products: HOXALIRA®50 MG/VIAL, HOXALIRA® 100 MG/ VIAL
  3. Drug

    Antihemophilic factor, human recombinant

    go.drugbank.com/drugs/DB00025
    ApprovedInvestigational

    Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells

    Products: KOGENATE-FS for Injection 500 iu/vial, KOGENATE-FS for Injection 250 iu/vial
  4. Drug

    Thrombin

    go.drugbank.com/drugs/DB11300
    ApprovedInvestigational

    Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which...

    Mixtures: TISSEEL FIBRIN SEALANT VH S/D (FROZEN), TACHOSİL 5,5 MG/CM2 İNSAN FİBRİNOJENİ VE 2.0 IU/CM2 İNSAN TROMBİNİ İLAÇLI SÜNGERProducts: Thrombinar Pws 5000unit/vial
  5. Drug

    Iron sucrose

    go.drugbank.com/drugs/DB09146
    ApprovedInvestigational

    Due to less side effects than iron dextran, iron sucrose is more preferred in chronic kidney disease patients. … saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do

    Mixtures: Poly-Vi-Flor with IronProducts: Venofer 20 mg/ml - Injektionslösung oder Konzentrat zur Herstellung einer Infusionslösung
  6. Drug

    Dactinomycin

    go.drugbank.com/drugs/DB00970
    ApprovedInvestigational

    A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termina...

    Synonyms: Actinomycin D, ACTINOMYCIN-DProducts: U. DACTINOMYCIN FOR INJECTION 0.5 mg/vial, ACTINOMICINA D INYECTABLE
  7. Drug

    Benzylpenicillin

    go.drugbank.com/drugs/DB01053
    ApprovedInvestigationalVet approved

    It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. … considered the drugs of choice for several infections caused by susceptible gram positive aerobic organisms, such as *Streptococcus pneumoniae*, groups A, B, C and G streptococci, nonenterococcal group D

    Mixtures: SENCAIN-S 100.000 IU/300.000 IU IM ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 FLAKON + 1 AMPUL, PROKAIN PENICILLIN 3.1.400.000 IU IM ENJEKSİYONLUK TOZ, 10 ADETProducts: PENICILLIN G SODIUM SANDOZ 5,000,000 IU/VIAL, PENICILLIN G SODIUM SANDOZ 1,000,000 IU/VIAL
  8. Drug

    Sodium molybdate

    go.drugbank.com/drugs/DB14496
    Approved

    Synonyms: Sodium molybdate(VI)Mixtures: VI-MINERAL 30 CIGNEME TABLETI, GENERADOR DE SOLUCION INYECTABLE DE PERTECNETATO (99MTC) DE SODIO. 2-50GBQ
  9. Drug

    Doxorubicin

    go.drugbank.com/drugs/DB00997
    ApprovedInvestigational

    Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970. Although they both have aglyconic and sugar moieties, doxor...

    Products: U. DOXORUBICIN HCL FOR INJECTION 50 mg/vial, U. DOXORUBICIN HCL FOR INJECTION 10 mg/vial
  10. Drug

    Dacarbazine

    go.drugbank.com/drugs/DB00851
    ApprovedInvestigational

    An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.

    Products: Dtic Dome Inj 200mg/vial, Dtic-dome -pws IV 200mg/vial