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Oxaliplatin
go.drugbank.com/drugs/DB00526ApprovedInvestigational[A797] Due to this chemical moiety, oxaliplatin readily undergoes non-enzymatic biotransformation, thus complicating oxaliplatin's pharmacokinetics. … [A260396] However, due to the structure of oxaliplatin, its adducts make the binding of mismatch repair protein to DNA harder compared to cisplatin or carboplatin's adducts, resulting in greater cytotoxic
Products: HOXALIRA®50 MG/VIAL, HOXALIRA® 100 MG/ VIALColistimethate
go.drugbank.com/drugs/DB01111ApprovedInvestigationalVet approvedColistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aer...
Products: COLIJECT ® 150 MG / VIAL, COLISTIMETATO 150MG/VIALEravacycline
go.drugbank.com/drugs/DB12329ApprovedInvestigationalEravacycline, known as Xerava by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of the tetracycline class with activity against clinically significant gram-negative, gram-positive aerobic, and facultative bacte...
Products: XERAVA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG PER VIALIndinavir
go.drugbank.com/drugs/DB00224ApprovedInvestigationalA potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Synonyms: (1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-pentonamideProducts: RETOR-VIDDactinomycin
go.drugbank.com/drugs/DB00970ApprovedInvestigationalA compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termina...
Synonyms: Actinomycin D, ACTINOMYCIN-DProducts: U. DACTINOMYCIN FOR INJECTION 0.5 mg/vial, ACTINOMICINA D INYECTABLETuroctocog alfa
go.drugbank.com/drugs/DB09109ApprovedTuroctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog a...
Products: NOVOEIGHT POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500IU/VIAL, NOVOEIGHT POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIALArbutin
go.drugbank.com/drugs/DB11217ApprovedIt is found in foods, over-the-counter drugs, and herbal dietary supplements [F43]. … Extracted from the dried leaves of bearberry plant in the genus _Arctostaphylos_ and other plants commonly in the _Ericaceae_ family, arbutin is a beta-D-glucopyranoside of [DB09526].
Mixtures: Dr G Whitening REFORMER by EGF, Dr G Whitening FORTIFIER by EGFSynonyms: p-hydroxyphenyl β-D-glucoside, hydroquinone O-β-D-glucopyranosideAflibercept
go.drugbank.com/drugs/DB08885ApprovedInvestigational[A261281,A261286] Due to the 2 fused VEGFR, aflibercept has a higher affinity to the cognate ligands than the endogenous individual receptor. … [L47976] An aflibercept biosimilar, Yesafili, was approved for use in the EU in September 2023.
Products: EYLEA SOLUTION FOR INJECTION IN VIAL 2MG, EYLEA 40MG/ML SOLUTION FOR INJECTION IN VIALMiconazole
go.drugbank.com/drugs/DB01110ApprovedVet approved[A214523, L14021] It is currently available as a variety of prescription and over the counter products.
Mixtures: Dg Health Miconazole 3, Dg Health Miconazole 3Products: DB Antifungal foot, Dg Health MiconazoleSpectinomycin
go.drugbank.com/drugs/DB00919ApprovedVet approvedWithdrawnAn antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Products: TROBICIN FOR INJECTION 2 g/vial