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Memantine
go.drugbank.com/drugs/DB01043ApprovedInvestigationalIn 2013, this number increased to 44 million. Almost doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and to 115 million by 2050 [F4366]. … Memantine blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and excessive stimulation in Alzheimer's Disease [T556].
Mixtures: MEGINGO 10/50 MG EFERVESAN TABLET, 100 ADET, MEGINGO 20/50 MG EFERVESAN TABLET, 100 ADETCategories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP2B6 InhibitorsEstradiol
go.drugbank.com/drugs/DB00783ApprovedInvestigationalVet approvedEthinyl estradiol is different from estradiol due to its higher biovailability and increased resistance to metabolism, rendering it more suitable for oral administration.
Synonyms: (17β)-estra-1,3,5(10)-triene-3,17-diol, 17β-estra-1,3,5(10)-triene-3,17-diolInternational brands: Estraderm MXBismuth subcitrate potassium
go.drugbank.com/drugs/DB09275ApprovedInvestigationalA bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).
Mixtures: KATACOLD 120 MG + 3.75 MG+ l MG /5 ML PEDIYATRIK ŞURUP, 100 ML, Pylera 140 mg/125 mg/125 mg HartkapselnProducts: NOTUSS 50 MG SR TABLET,10 TABLET, KAF 7,5 MG / 5 ML SURUP, 100 MLAmoxicillin
go.drugbank.com/drugs/DB01060ApprovedInvestigationalVet approved[A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum concentrations than ampicillin. … Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.
Synonyms: (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidMixtures: KLAMOKS 125 MG + 31,25 MG /5 ML PEDİATRİK 100 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 100 ML, AUGMENTİN 400 MG+57 MG/5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 100 MLEvorpacept
go.drugbank.com/drugs/DB17573InvestigationalEvorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).
Synonyms: A CD47-binding, fusion protein containing a high affinity engineered D1 domain of human signal regulatory protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domainAnti-SARS-CoV-2 immunoglobulin
go.drugbank.com/drugs/DB16360InvestigationalHyperimmune immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and develop neutralizing antibodies. … [L27521] Anti-coronavirus immunoglobulin is derived from [COVID-19 convalescent plasma](https://go.drugbank.com/drugs/DB15692) but contains more SARS-CoV-2 neutralizing antibodies than found in [convalescent
Synonyms: Hyperimmune immunoglobulin to SARS-CoV-2Categories: Immunoglobulin GFentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approvedFentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. … [A179542] Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesProducts: FENTANEST 500 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ (10 ADET), FENTANYL 0,05 MG/ML 10 ML SOLÜSYON İÇEREN IV AMPUL, 50 ADETTheophylline
go.drugbank.com/drugs/DB00277ApprovedInvestigationalA methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine recep...
Mixtures: THEOLONG 1200/400 MG EFERVESAN TABLET, 10 ADET, THEOLONG 600/200 MG EFERVESAN TABLET, 10 ADETCategories: Phosphodiesterase 5 Inhibitors, Cytochrome P-450 SubstratesPotassium chloride
go.drugbank.com/drugs/DB00761ApprovedInvestigationalWithdrawnThe FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release … dosage forms and those products formulated for preparation of solution prior to ingestion.
Mixtures: SODIO60 MCG +POTASIO 20 MCG + CLORURO 50 MCG + CITRATO 30 MG + GLUCOSA111 MCG, LITORAL TOZ, 50 ADETInternational brands: Kaon-CL 10Amphotericin B
go.drugbank.com/drugs/DB00681ApprovedInvestigationalconcentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. … While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B.
Products: AMPHOLIP ®50 MG/10 ML, AMBISOME 50 MG IV INFUZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 10 ADET