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Propofol
go.drugbank.com/drugs/DB00818ApprovedInvestigationalVet approvedIV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. … Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia.
Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesInternational brands: IV-ProIsosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigationalIsosorbide mononitrate is an organic nitrate with vasodilating properties. … Like other organic nitrates, isosorbide mononitrate acts as a prodrug for its active metabolite, [nitric oxide], which mediates the therapeutic action of isosorbide mononitrate.
Products: ISMN AL 20, ISMN AL 40Quercus virginiana pollen
go.drugbank.com/drugs/DB10375ApprovedQuercus virginiana pollen is the pollen of the Quercus virginiana plant. Quercus virginiana pollen is mainly used in allergenic testing.
Products: Center-AL - Quercus Virginiana PollenMetformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalIt is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.
Mixtures: Ag-sitagliptin Hydrochloride / Metformin, Ag-sitagliptin Hydrochloride / MetforminProducts: KETAMET-PR, Pg-metforminTretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceuticalTretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol). … [A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism.
Synonyms: Vitamin A acid, all-trans-Vitamin A acidInternational brands: Stieva-AFamotidine
go.drugbank.com/drugs/DB00927ApprovedInvestigationaldisease, famotidine was about 20 to 50 times more potent at inhibiting gastric acid secretion than [cimetidine] and eight times more potent than [ranitidine] on a weight basis. … Famotidine is a competitive histamine-2 (H<sub>2</sub>) receptor antagonist that works to inhibit gastric acid secretion.
International brands: Mylanta ARCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. … [A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: Glyrx-PF, GLYCO-PPramipexole
go.drugbank.com/drugs/DB00413ApprovedInvestigationalPramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). … It is a _non-ergot dopamine agonist_ drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement) [A176867].
Products: Ava-pramipexole, PRAMIPEXOL AL 2.1MG RETAgrostis gigantea top
go.drugbank.com/drugs/DB14757ApprovedWithdrawnAgrostis gigantea top is the flowering part of the Agrostis gigantea plant. Agrostis gigantea top is mainly used in allergenic testing.
Products: Center-AL - Agrostis GiganteaMorphine
go.drugbank.com/drugs/DB00295ApprovedInvestigational[A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Astramorph PF, MORPHIN AL 10 RETARD