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Sonidegib
go.drugbank.com/drugs/DB09143ApprovedInvestigationalSonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substratesp-Fluorofentanyl
go.drugbank.com/drugs/DB09177ExperimentalIllicitp-Fluorofentanyl is an opioid analgesic being an analogue of fentanyl developed by Janssen Pharmaceutica in the 1960s. p-Fluorofentanyl was sold briefly on the US black market in the early 1980s, before … introduction of the Federal Analog Act which for the first time attempted to control entire families of drugs based on their structural similarity rather than scheduling each drug individually as they appeared. p-Fluorofentanyl
Viloxazine
go.drugbank.com/drugs/DB09185ApprovedInvestigationalWithdrawnViloxazine is a selective norepinephrine reuptake inhibitor. For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. It was first approved in the UK in 1974; however, the immediate-releas...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsLorpiprazole
go.drugbank.com/drugs/DB09195ApprovedLorpiprazole is a serotonin antagonist and reuptake inhibitor used for the treatment of major depressive disorder. It is a piperazinyl-triazole derivative.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesNetoglitazone
go.drugbank.com/drugs/DB09199ExperimentalNetoglitazone (MCC-555) is a hypoglycemic agent.
Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 SubstratesSynephrine
go.drugbank.com/drugs/DB09203InvestigationalSynephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. … It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine.
Synonyms: p-synephrineArotinolol
go.drugbank.com/drugs/DB09204InvestigationalArotinolol is an alpha- and beta-receptor blocker developed in Japan. It is a thiopropanolamine with a tertiary butyl moiety. It has been studied for its potential to be an antihypertensive therapy. Artinolol is being developed by Sumito...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesFibrinogen human
go.drugbank.com/drugs/DB09222ApprovedInvestigationalFibrinogen concentrate (human) is a hematological agent. It works by replacing a specific protein in the blood, fibrinogen (factor I), that helps with blood clotting. It is a soluble plasma glycoprotein with a molecular weight of about 3...
Mixtures: BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI, BERIPLAST-P COMBI SET 3 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICIProducts: HAEMOCOMPLETTAN P POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL, HAEMOCOMPLETTAN-P 1G IV ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ TOZUZotepine
go.drugbank.com/drugs/DB09225ApprovedWithdrawnZotepine, with the formula (2-chloro-11-(2-dimethyl-amino-ethoxy)-dibenzo thiepin, is a neuroleptic drug. It was designed and synthesized by Fujisawa Pharmaceutical Co Ltd. It has been used as an antipsychotic in Japan, India and some pl...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAranidipine
go.drugbank.com/drugs/DB09229ExperimentalAranidipine is a novel dihydropyridine derivative that gives rise to two active metabolites (M-1α and M-1β) that exhibit hypotensive activity. It is a calcium antagonist with the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-n...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates