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Displaying results 1801 - 1810 of 10000 in total
  1. Target

    Serine/threonine-protein kinase Nek5

    go.drugbank.com/bio_entities/BE0009499
    TargetHumans

    Synonyms: Never in mitosis A-related kinase 5
  2. Target

    Chloride anion exchanger

    go.drugbank.com/bio_entities/BE0010211
    TransporterHumans

    Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation (By similarity) … Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia (PubMed:16606687, PubMed:19321737, PubMed:22159084, PubMed:22627094).

    Synonyms: Down-regulated in adenoma
  3. Target

    Serine/threonine-protein kinase Nek7

    go.drugbank.com/bio_entities/BE0017593
    TargetHumans

    Protein kinase which plays an important role in mitotic cell cycle progression (PubMed:17101132, PubMed:19941817, PubMed:31409757). … Phosphorylates EML4 at 'Ser-146', promoting its dissociation from microtubules during mitosis which is required for efficient chromosome congression (PubMed:31409757).

    Synonyms: Never in mitosis A-related kinase 7
  4. Drug

    Margetuximab

    go.drugbank.com/drugs/DB14967
    ApprovedInvestigational

    [A225751, A225756, A225766, A191829, L27986] Margetuximab binds to the same epitope on the HER2 extracellular domain and induces the same effects as [trastuzumab]. … [A225756] Margetuximab (formerly MGAH22) is an Fc-engineered human/mouse chimeric anti-HER2 IgG1κ monoclonal antibody derived from the same mouse 4D5 clone that [trastuzumab] is derived from and is

  5. Drug

    Tazarotene

    go.drugbank.com/drugs/DB00799
    Approved

    It is a prodrug that is found in topical formulations used in the treatment of various conditons, such as psoriasis, acne, and sun damaged skin (photodamage). … Tazarotene, commonly marketed as Tazorac®, Avage®, and Zorac®, is member of the acetylenic class of retinoids.

    Mixtures: Hyaluronic Acid Sodium Salt 0.5% / Tazarotene 0.1%, Hyaluronic Acid Sodium Salt 0.5% / Tazarotene 0.05%Categories: Antipsoriatics for Topical Use
  6. Drug

    DL-dimyristoylphosphatidylcholine

    go.drugbank.com/drugs/DB11283
    Approved

    A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. It is used in commercial drug preparations to solubilize drugs for injection [A32711]

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Eliglustat

    go.drugbank.com/drugs/DB09039
    ApprovedInvestigational

    The results of this test dictate eliglustat dosing recommendations for each type of patient. There are no dosing recommendations for CYP2D6 ultra-rapid or indeterminate metabolizers. … [L41404,A7634] Eliglustat was approved by the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 Gaucher disease.

    Synonyms: N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamide
  8. Drug

    Norethindrone enanthate

    go.drugbank.com/drugs/DB14678
    Investigational

    Categories: Hormonal Contraceptives for Systemic UseProducts: NORISTERAT INJ 200MG/ML (SYRINGE)
  9. Drug

    Mertiatide

    go.drugbank.com/drugs/DB15780
    Investigational

    Products: Mertioscan 0,2 mg Kit für ein radioaktives Arzneimittel
  10. Drug

    Coagulation factor VII human

    go.drugbank.com/drugs/DB13150
    ApprovedInvestigational

    Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.

    Mixtures: BERIPLEX P/N 500 POWDER FOR SOLUTION FOR INJECTION, OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IUCategories: coagulation factor IX, II, VII and X in combination