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Displaying results 1801 - 1810 of 10000 in total
  1. Drug

    Oxymetazoline

    go.drugbank.com/drugs/DB00935
    ApprovedInvestigational

    Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α<sub>1</sub>- and α<sub>2</sub>-adrenoceptors. … [L15057] In July 2020, the FDA approved the use of an ophthalmic formulation of oxymetazoline (Upneeq) in adults with acquired blepharoptosis, or ptosis, making it the first FDA-approved medical treatment

    Mixtures: N-S-4Categories: Adrenergic alpha-2 Receptor Agonists, Cytochrome P-450 Substrates
  2. Drug

    Prednicarbate

    go.drugbank.com/drugs/DB01130
    Approved

    It is used in the treatment of inflammatory skin diseases, such as atopic dermatitis. … IL-1a is also found in fibroblasts, where it is responsible for proliferation, collagenase induction and IL-6 synthesis, which are related to skin thickness.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersInternational brands: Dermatop E Emollient
  3. Drug

    Pine tar

    go.drugbank.com/drugs/DB15840
    ApprovedWithdrawn

    Products: Psoriasol 500, WILKINSON POMAD %12.5 100 GR
  4. Drug

    Arginine

    go.drugbank.com/drugs/DB00125
    ApprovedInvestigationalNutraceutical

    An essential amino acid that is physiologically active in the L-form.

    Mixtures: VAMIN 14 EF ELEKTROLITSIZ AMINOASİT SOLÜSYON, 500 ML, POLİNUTHREE EN-550 ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ, VE LİPİD EMÜLSİYONU, 1000 MLSynonyms: (2S)-2-amino-5-guanidinopentanoic acid, (2S)-2-amino-5-(carbamimidamido)pentanoic acid
  5. Drug

    Lenacapavir

    go.drugbank.com/drugs/DB15673
    ApprovedInvestigational

    [L42995] On December 22, 2022, it was also approved by the FDA.[L44473] … [A244170, A244175, A244180, A244190] Lenacapavir was first globally approved on August 22, 2022 by the European Commission to treat adults with multi-drug resistant HIV infection.

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: N-((1S)-1-(3-(4-CHLORO-3-(METHANESULFONAMIDO)-1-(2,2,2-TRIFLUOROETHYL)-1H-INDAZOL-7-YL)-6-(3-(METHANESULFONYL)-3-METHYLBUT-1-YN-1-YL)PYRIDIN-2-YL)-2-(3,5- DIFLUOROPHENYL)ETHYL)-2-((3BS,4AR)-5,5-DIFLUORO, DIFLUOROPHENYL)ETHYL)-5,5-DIFLUORO-3B,4,4A,5-TETRAHYD
  6. Drug

    HEPES

    go.drugbank.com/drugs/DB16872
    Investigational

    Categories: Compounds used in a research, industrial, or household settingSynonyms: HEPES, 4-(2-Hydroxyethyl)-1-piperazineethane sulfonic acid
  7. Drug

    Binimetinib

    go.drugbank.com/drugs/DB11967
    ApprovedInvestigational

    [A34275,L3335] On June 27, 2018, the Food and Drug Administration approved the combination of [Encorafenib] and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients … Binimetinib, also known as _Mektovi_, is a potent and selective oral mitogen-activated protein kinase 1/2 (MEK 1/2) inhibitor which is combined with [Encorafenib].

    Categories: Heterocyclic Compounds, 2-Ring, MAP Kinase Kinase 2, antagonists & inhibitorsProducts: Mektovı 15 mg Film Kaplı Tablet, 84 ADET, MEKTOVI® 15 MG TABLETAS RECUBIERTAS
  8. Drug

    Reboxetine

    go.drugbank.com/drugs/DB00234
    ApprovedInvestigationalWithdrawn

    Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. … Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: EDRONAX 4 MG TABLET, 60 ADET, Edronax 4 mg - Tabletten
  9. Drug

    Helium

    go.drugbank.com/drugs/DB09155
    ApprovedInvestigationalVet approved

    Helium is a second most abundant chemical element in the universe with symbol He and atomic number 2. … It is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas located at the top of the noble gases on the periodic table.

    Mixtures: Helium Oxygen Mix 80/20, Helium/Oxygen Mixture 80/20Products: Helium 100%
  10. Drug

    Candesartan

    go.drugbank.com/drugs/DB13919
    Investigational

    Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of [candesartan cilexetil].

    Mixtures: EUROPRES - D 16 MG / 12.5 MG TABLETA., CANDESARTAN E IDROCLOROTIAZIDE EGCategories: Agents Acting on the Renin-Angiotensin System, Angiotensin 2 Receptor Blocker