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Latanoprost
go.drugbank.com/drugs/DB00654ApprovedInvestigationalLatanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment.
Mixtures: Tim-Dor-Lat, Tim-Brim-Dor-LatCategories: Compounds used in a research, industrial, or household settingMometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedMometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295]. … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295].
Categories: Corticosteroids for inhalation use, Drugs for Obstructive Airway DiseasesCalcium threonate
go.drugbank.com/drugs/DB11168ApprovedWithdrawnThe most common form is calcium L-threonate, or (2R,3S)-2,3,4-trihydroxy butyric acid calcium [A27266]. … Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement [A27266].
Finerenone
go.drugbank.com/drugs/DB16165ApprovedInvestigational[A236544] Spironolactone has low selectivity and affinity for the receptor; it dissociates quickly and can also have effects at the androgen, progesterone, and glucocorticoid receptors. … [A236544] So far, finerenone is the only nonsteroidal mineralocorticoid receptor antagonist to be FDA approved.
Fitusiran
go.drugbank.com/drugs/DB15002ApprovedInvestigational[L52860] Fitusiran was first approved by the FDA on March 28, 2025, as routine prophylaxis therapy to prevent or reduce the frequency of bleeding episodes associated with hemophilia A or B.
Apomorphine
go.drugbank.com/drugs/DB00714ApprovedInvestigational[A203618] Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and a treatment of other movement disorders.
Categories: Heterocyclic Compounds with 4 or More RingsMK-4721
go.drugbank.com/drugs/DB05933Investigationalfully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell Antigen (PSCA), an antigen expressed at significant levels on tumor cells from the majority of patients with all
Canagliflozin
go.drugbank.com/drugs/DB08907ApprovedInvestigationalIt was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 for a second indication of reducing the risk of cardiovascular events in patients diagnosed with type … Canagliflozin is the first oral antidiabetic drug approved for the prevention of cardiovascular events in patients with type 2 diabetes [L5897].
Promethazine
go.drugbank.com/drugs/DB01069ApprovedInvestigational[A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.
Categories: Antihistamines for Topical Use, Antihistamines for Systemic UseDemeclocycline
go.drugbank.com/drugs/DB00618ApprovedBecause it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Categories: Antibiotics for Topical Use, Antibacterials for Systemic Use