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Streptococcus pneumoniae type 14 capsular polysaccharide antigen
go.drugbank.com/drugs/DB10332ApprovedInvestigationalIt is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Mixtures: PREVENAR 13 SUSPENSION FOR INJECTION, Prevenar 13 Suspension For InjectionBrexpiprazole
go.drugbank.com/drugs/DB09128ApprovedInvestigationalIt has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. … [L46417] Although it is structurally similar to [aripiprazole], brexpiprazole has different binding affinities for dopamine and serotonin receptors.
Categories: Antidepressive Agents Indicated for DepressionCarbazochrome
go.drugbank.com/drugs/DB09012ApprovedWithdrawnCarbazochrome has been investigated for use in the treatment of non-surgical acute uncomplicated hemorrhoids in a mixture with [DB13124], and this combination therapy demonstrated efficacy and safe tolerability … either at a local or systemic level [A19744].
International brands: Hemosin K, Ophthalm KHexylresorcinol
go.drugbank.com/drugs/DB11254ApprovedIt can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic.
Molnupiravir
go.drugbank.com/drugs/DB15661Investigational[A193014,A193026] With improved oral bioavailability in non-human primates, it is hydrolyzed _in vivo_, and distributes into tissues where it becomes the active 5’-triphosphate form. … Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of [N4-hydroxycytidine].
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UsePerindopril
go.drugbank.com/drugs/DB00790ApprovedInvestigationalPerindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). … Perindopril may be used to treat mild to moderate essential hypertension, mild to moderate congestive heart failure, and to reduce the cardiovascular risk of individuals with hypertension or post-myocardial
Mixtures: NORMOTRİ FORT 5 MG/2.5 MG/8.14 MG FİLM KAPLI TABLET, 30 ADET, NORMOTRİ FORT 10 MG/2.5 MG/8.14 MG FİLM KAPLI TABLET, 30 ADETCategories: Antihypertensive Agents Indicated for HypertensionInterferon Kappa
go.drugbank.com/drugs/DB15749ExperimentalThis gene encoding for this interferon is expressed in human epidermal keratinocytes. … Interferon kappa is a subclass of type I interferon mediating host defence which consists of 207 amino acids and has 30% homology with others of the same class as it consists of a series of cysteine and
Raxtozinameran
go.drugbank.com/drugs/DB18228ApprovedInvestigationalRaxtozinameran is also known as Pfizer-BioNTech COVID-19 Vaccine and Comirnaty. It works by binding to the spike (S) protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which is a transmembrane glycoprotein that play...
Telithromycin
go.drugbank.com/drugs/DB00976ApprovedBinding occurs simultaneously at to two domains of 23S RNA of the 50S ribosomal subunit, domain II and V, where older macrolides bind only to one.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseEfgartigimod alfa
go.drugbank.com/drugs/DB15270ApprovedInvestigationalEfgartigimod alfa for intravenous use was granted FDA approval on December 17, 2021[L39501] and European Commission approval on August 11, 2022 for use in patients with myasthenia gravis. … [L43190] A formulation for subcutaneous use that combines efgartigimod alfa and hyaluronidase was later approved for the treatment of patients with chronic inflammatory demyelinating polyneuropathy (CIDP