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Displaying results 1811 - 1820 of 10000 in total
  1. Drug

    (3-EXO)-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8,8-DIMETHYL-8-AZONIABICYCLO[3.2.1]OCTANE

    go.drugbank.com/drugs/DB07494
    Experimental

    Synonyms: (3-EXO)-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8,8-DIMETHYL-8-AZONIABICYCLO[3.2.1]OCTANE
  2. Drug

    Cinchocaine

    go.drugbank.com/drugs/DB00527
    ApprovedVet approved

    A local anesthetic of the amide type now generally used for surface anesthesia. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)

    Mixtures: ULTRAPROCT %0,09+%0,09+%0,5 MERHEM, 10 G, Dibucaine HCl 0.5% / Lidocaine 15% / Phenylephrine HCl 1% / Prilocaine 5%Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Desmethylprodine

    go.drugbank.com/drugs/DB01478
    ExperimentalIllicit

    It has been listed as a Schedule I controlled drug in the United States, and thus is not used clinically. It is known to be a designer drug, synthesized in 1977, for the purpose of recreational use. … Desmethylprodine, a derivative of meperidine, is an opioid analgesic with the potency of morphine.

    Categories: Cytochrome P-450 CYP2D6 Inhibitors, Heterocyclic Compounds, 1-RingSynonyms: 1-Methyl-4-phenyl-4-piperidinol propionate, 1-Methyl-4-phenyl-4-propionoxypiperidine
  4. Drug

    Midecamycin

    go.drugbank.com/drugs/DB13456
    Investigational

    In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position 4 of the terminal sugar. … Midecamycin is a naturally occurring 16-membered macrolide [A33072] that fits under the category of acetoxy-substituted macrolide antibiotics.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: Espinomycin A, Medemycin A1
  5. Drug

    Moxonidine

    go.drugbank.com/drugs/DB09242
    ApprovedInvestigationalWithdrawn

    Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. … As well, moxonidine has been shown to present blood pressure-independent beneficial effects on insulin resistance syndrome.

    Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-2 Receptor AgonistsSynonyms: (2R,4R)-1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8- quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid
  6. Drug

    Ivonescimab

    go.drugbank.com/drugs/DB18931
    Investigational

    Ivonescimab is under investigation in clinical trial NCT05184712 (Phase 3 Clinical Study of AK112 for NSCLC Patients).

    Synonyms: IMMUNOGLOBULIN G1 (240-ALANINE,241-ALANINE), ANTI-(HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR A) (HUMAN-MUS MUSCULUS MONOCLONAL AK112 .GAMMA.1-CHAIN) FUSION PROTEIN WITH PEPTIDE LINKER (GGGS)4 FUSION PROTEIN
  7. Drug

    Raxtozinameran

    go.drugbank.com/drugs/DB18228
    ApprovedInvestigational

    It works by binding to the spike (S) protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which is a transmembrane glycoprotein that plays a vital role in viral pathogenesis, evolutions … [A273680] Raxtozinameran was first approved by the FDA and EMA through emergency use in December 2020.[L52565,L39272]

    Synonyms: RBP-020.2 4 (XBB.1.5 variant), RNA (recombinant 5′-[1,2-[(3′-O-methyl)m7G-(5′→5′)-ppp-Am]]-capped all uridine→N1-methylpseudouridine-substituted severe acute respiratory syndrome coronavirus 2 spike glycoprotein secretory signal peptideProducts: COMIRNATY® VACUNA DE ARNM CONTRA COVID-19
  8. Drug

    Naporafenib

    go.drugbank.com/drugs/DB18865
    Investigational

    Naporafenib is under investigation in clinical trial NCT06346067 (A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With Nras-mutant Melanoma (SEACRAFT-2)).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-pyridinecarboxamide, n-(3-(2-(2-hydroxyethoxy)-6-(4-morpholinyl)-4-pyridinyl)-4-methylphenyl)-2-(trifluoromethyl)-)-, N-(3-(2-(hydroxyethoxy)-6-(morpholin-4-yl) pyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)pyridine-4-carboxamide
  9. Drug

    3,4-Biphenyldiol

    go.drugbank.com/drugs/DB07478
    Experimental

    Synonyms: 4-Phenylcatechol, 4-Phenylpyrocatechol
  10. Drug

    FK352B

    go.drugbank.com/drugs/DB06484
    Experimental

    FK352B is a adenosine A1 antagonist that is developed for the treatment of dialysis-induced hypotension.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-((2R)-1-((2E)-3-(2-PHENYLPYRAZOLO(1,5-A)PYRIDIN-3-YL)PROP-2-ENOYL)PIPERIDIN-2-YL)ACETIC ACID, 2-PIPERIDINEACETIC ACID, 1-((2E)-1-OXO-3-(2-PHENYLPYRAZOLO(1,5-A)PYRIDIN-3-YL)-2-PROPEN-1-YL)-, (2R)-