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Eluxadoline

of both pain and diarrhea characteristic of IBS-D. … Agonism of peripheral mu-opioid receptors results in reduced colonic motility, while antagonism of central delta-opioid receptors results in improved analgesia, making eluxadoline usable for the symptoms

Rezafungin

[A258403] In March 2023, the FDA approved rezafungin for injection for the treatment of candidemia and invasive candidiasis in adults with limited or no alternative treatment options. … [L45633,L45658] It was subsequently approved in the EU in November of the same year. [L52745]

Avelumab

It is used in the treatment of Merkel cell carcinoma, metastatic urothelial carcinoma, or renal cell carcinoma. … [A261496] On September 18 and December 18 of the same year, it was also granted approval by EMA [L48126] and Health Canada,[L48171] respectively.

Chloramphenicol

specific route of administration. … An antibiotic first isolated from cultures of _Streptomyces venezuelae_ in 1947 but now produced synthetically.

Heme iron polypeptide

Pralatrexate

Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma [L37674]. … [A246703] Pralatrexate was approved by the FDA on September 24, 2009.

Imidacloprid

Imidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine. … Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and sold under trade names Kohinor, Admire, Advantage, Gaucho, Merit, Confidor, Hachikusan, Premise

Etrasimod

efficacy of a 2-mg daily dose regimen of etrasimod, with a 32% and 26% remission rate observed in UC 52 and UC 12 trials respectively. … [L48501] The European Commission also approved the marketing of etrasimod on February 19, 2024.[L50998]

Potassium alum

Potassium alum is formed by large, transparent crystals that are used in different products like food or drugs as a buffer, neutralizing or forming agent.[T60] … [L1070] It is an inorganic salt, also called potassium aluminum sulfate with a formula of AlK(SO4)2 that is predominantly produced in the dodecahydrate form (AlK(SO4)2 * 12H2O).

Cyclobenzaprine

Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepre...