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Atacicept
go.drugbank.com/drugs/DB06399ApprovedInvestigationalAtacicept is a recombinant fusion glycoprotein that joins the ligand-binding portion of the human TACI receptor to a modified IgG1 Fc domain, allowing it to bind and neutralize two cytokines: B cell activating … factor (BAFF) and A Proliferation Inducing Ligand (APRIL).
Categories: Amino Acids, Peptides, and ProteinsSynonyms: Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein (Fc5)Zenocutuzumab
go.drugbank.com/drugs/DB15559ApprovedInvestigational[A264833] On December 4, 2024, the FDA granted accelerated approval to zenocutuzumab for the treatment of non-small cell lung cancer and pancreatic adenocarcinoma. … [L51963] It works to attenuate aberrant cancer cell growth caused by genomic rearrangements involving the neuregulin 1 gene (NRG1), which is an oncogenic driver.
Categories: Amino Acids, Peptides, and ProteinsSynonyms: Mcla-128 (igg1 bispecific antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and her3 receptors.), Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized clone mcla-128 .gamma.1-chain), disulfide with humanized clone mcla-128 light chain, dimerNiacin
go.drugbank.com/drugs/DB00627ApprovedInvestigationalNutraceuticalNiacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.
Synonyms: Nicotinic acid, 3-Pyridinecarboxylic acidMixtures: Folivane-Plus with Ascorbic Acid Precursors, Niacin 500 Mg and InositolDiatrizoate
go.drugbank.com/drugs/DB00271ApprovedVet approvedAs diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Synonyms: Urografin acid, Diatrizoic acidSalts: Diatrizoic acid dihydrateFoscarnet
go.drugbank.com/drugs/DB00529ApprovedInvestigationalAn antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Synonyms: Carboxyphosphonic acid, Phosphonoformic acidCategories: Phosphonic Acid Derivatives, Acids, AcyclicOteracil
go.drugbank.com/drugs/DB03209ApprovedInvestigationalOteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. … By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, 5-FU is able to insert itself into strands of DNA and RNA, thereby halting the replication process necessary
Synonyms: Oxonic Acid, 5-azaorotic acidIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigationalIbuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin.
Synonyms: 4-isobutylhydratropic acid, (±)-p-isobutylhydratropic acidMixtures: Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17%, STOP DOL COMPUESTO CAPSULAS BLANDASTalquetamab
go.drugbank.com/drugs/DB16678ApprovedInvestigational[L47765] Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and CD3 on T cells. … It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: ANTIBODY; BISPECIFIC GAMMA4 HEAVY CHAIN HUMANIZED AN, IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONALColistimethate
go.drugbank.com/drugs/DB01111ApprovedInvestigationalVet approvedColistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms.
Categories: Amino Acids, Peptides, and Proteins, Pore Forming Cytotoxic ProteinsSynonyms: Colistin methanesulfonic acid, Colistinmethanesulfonic acidIbandronate
go.drugbank.com/drugs/DB00710ApprovedInvestigationalIbandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and [risedronic acid]. … [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs.
Categories: ibandronic acid and colecalciferol, ibandronic acidSynonyms: Ibandronic acid