Search

Displaying results 181 - 184 of 184 in total
  1. Target

    Atrial natriuretic peptide receptor 3

    go.drugbank.com/bio_entities/BE0002426
    TargetHumans

    Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production … May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects.

    Synonyms: ANP-C
  2. Target

    ADP/ATP translocase 2

    go.drugbank.com/bio_entities/BE0000709
    TargetHumans

    Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1.5 kDa, and which contributes to cell death (PubMed:31883789). … ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity).

    Synonyms: ANT 2
  3. Target

    ADP/ATP translocase 1

    go.drugbank.com/bio_entities/BE0000599
    TargetHumans

    Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1.5 kDa, and which contributes to cell death (PubMed:31883789). … In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity (PubMed:31883789).

    Synonyms: ANT 1
  4. Target

    Sulfotransferase

    go.drugbank.com/bio_entities/BE0009567
    EnzymeTargetHumans

    Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones … Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands (PubMed:14573603, PubMed:18042734

    Synonyms: STM