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Isatuximab
go.drugbank.com/drugs/DB14811ApprovedInvestigational[L12099] It is a cytolytic antibody targeted against CD38, a glycoprotein found on the surface of some immune cells that is highly expressed by malignant plasma cells in multiple myeloma. … Isatuximab (formerly SAR650984) is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line.
Products: Sarclisa Sc, SARCLİSA 100 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETNicardipine
go.drugbank.com/drugs/DB00622ApprovedInvestigationalA potent calcium channel blockader with marked vasodilator action. … It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Cardene SR, CARDIBLOC-SR CAPSULE 40 mgProbenecid
go.drugbank.com/drugs/DB01032ApprovedInvestigationalThe prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubu...
Categories: Cytochrome P-450 CYP2C8 Inducers, Cytochrome P-450 CYP3A InducersSynonyms: 4-(Di-n-propylsulfamoyl)benzoesäure, 4-(N,N-Dipropylsulfamoyl)benzoesäureMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalDiabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. … [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GERD).
Mixtures: CLIFAR® GOTAS, PLASIL®ENZIMATICOCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesAmbrosia artemisiifolia pollen
go.drugbank.com/drugs/DB10385ApprovedAmbrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.
Mixtures: 3-ragweed Mix, Giant/short/western PollenProducts: RAGWIZAX 12 SQ-Amb Lyophilisat zur sublingualen AnwendungHypromellose
go.drugbank.com/drugs/DB11075ApprovedInvestigationalHypromellose is also found in eye drops as a lubricant [L1803]. … It is a commonly used as a delivery component in oral pharmaceutical products that provides the release of a drug in a controlled fashion, effectively increasing the duration of release of a drug to prolong
Synonyms: Cellulose, 2-hydroxypropyl methyl etherSalts: Hypromellose 2910 (3 mPa.S)Carbamoylcholine
go.drugbank.com/drugs/DB00411ApprovedCarbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. … [A226315] Carbamoylcholine was initially used as a treatment for migraines,[A226365] induction of diuresis,[A226370] and other parasympathetic effects.
Categories: Compounds used in a research, industrial, or household settingProducts: Carbachol Injection Liq Sc 0.25mg/ml, Isopto Carbachol 3%Indomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalNSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole … Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties.
Synonyms: 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acidInternational brands: Indolar SRSulfaquinoxaline
go.drugbank.com/drugs/DB11464ExperimentalVet approvedSulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K as
Products: TP-SQ 250 WSP Sulfaquinoxaline 250 mg/g Powder, SN ANTI-COCCI 45 mg/ml ORAL SOLUTIONMepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalThe pathogenesis of eosinophilia is complex, but IL-5 is recognized as a key cytokine involved in the differentiation, recruitment, activation, and prolonged survival of eosinophils in peripheral tissue … Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm<sup>3</sup> or more) is associated with a spectrum
Categories: Interleukin-5 AntagonistProducts: NUCALA 100 MG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, NUCALA 100 MG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 3 ADET