Ambrosia artemisiifolia pollen

Identification

Summary

Ambrosia artemisiifolia pollen is an extract from Ambrosia artemisiifolia pollen used in allergy testing.

Brand Names

Ragwitek

Generic Name

Ambrosia artemisiifolia pollen

DrugBank Accession Number

DB10385

Background

Ambrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.

Type

Biotech

Groups

Approved

Biologic Classification

Allergenics
Allergen Extract

Synonyms

• Ambrosia artemisiifolia
• short ragweed pollen extract
• short ragweed pollen extracts
• Standardized short ragweed pollen allergenic extract

Pharmacology

Indication

Ambrosia artemisiifolia pollen is an allergen extract indicated as immunotherapy for the treatment of short ragweed pollen-induced allergic rhinitis, with or without conjunctivitis, confirmed by positive skin test or in vitro testing for pollen-specific IgE antibodies for short ragweed pollen. It is approved for use in persons five through 65 years of age.

This allergen extract is not indicated for the immediate relief of allergic symptoms.¹

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Associated Conditions

• Allergic Rhinitis (AR)
• Allergy to Tree Pollen
• Asthma

Associated Therapies

• Immunotherapy

Contraindications & Blackbox Warnings

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Pharmacodynamics

Not Available

Mechanism of action

Not Available

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism

Not Available

Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects

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Toxicity

Not Available

Pathways

Not Available

Pharmacogenomic Effects/ADRs

Not Available

Interactions

Drug Interactions

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

Not Available

Food Interactions

Not Available

Products

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Brand Name Prescription Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End	Region	Image
Ambrosia Artemisiifolia Pollen	Injection, solution	0.05 g/1mL	Subcutaneous	ALK-Abello, Inc.	1965-01-01	Not applicable
Ambrosia Artemisiifolia Pollen	Injection, solution	40000 [PNU]/1mL	Subcutaneous	ALK-Abello, Inc.	1965-01-01	2021-11-30
Ambrosia Artemisiifolia Pollen	Injection, solution	0.10 g/1mL	Subcutaneous	ALK-Abello, Inc.	1965-01-01	Not applicable
Ambrosia Artemisiifolia Pollen	Injection, solution	20000 [PNU]/1mL	Subcutaneous	ALK-Abello, Inc.	1965-01-01	Not applicable
Center-AL - Ambrosia Artemisiifolia Pollen	Injection, suspension	10000 [PNU]/1mL	Subcutaneous	ALK-Abello, Inc.	1975-01-15	2023-05-16
Center-AL - Ambrosia Artemisiifolia Pollen	Injection, suspension	20000 [PNU]/1mL	Subcutaneous	ALK-Abello, Inc.	1975-01-15	Not applicable
Pollens - Weeds and Garden Plants, Short Ragweed, Ambrosia artemisiifolia	Injection, solution	0.05 g/1mL	Percutaneous; Subcutaneous	Jubilant Hollisterstier Llc	1977-10-18	Not applicable
Pollens - Weeds and Garden Plants, Short Ragweed, Ambrosia artemisiifolia	Injection, solution	500 [PNU]/1mL	Intradermal	Jubilant Hollisterstier Llc	1977-10-18	2022-03-01
Ragwitek	Tablet	12 [Amb'a'1'U]/1	Sublingual	Merck Sharp & Dohme Corp.	2014-04-17	2017-08-18
Ragwitek	Tablet	12 [Amb'a'1'U]/1	Sublingual	ALK-Abello A S	2014-04-17	Not applicable

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
3-ragweed Mix, Giant/short/western Pollen	Ambrosia artemisiifolia pollen (0.34 g/20mL) + Ambrosia psilostachya pollen (0.33 g/20mL) + Ambrosia trifida pollen (0.33 g/20mL)	Injection, solution	Percutaneous; Subcutaneous	Allergy Laboratories, Inc.	1967-12-07	Not applicable
Mixed Ragweed	Ambrosia artemisiifolia pollen (0.1 g/1mL) + Ambrosia trifida pollen (0.1 g/1mL)	Injection, solution	Percutaneous; Subcutaneous	ALK-Abello, Inc.	2015-05-03	Not applicable
Mixed Ragweed	Ambrosia artemisiifolia pollen (20000 [PNU]/1mL) + Ambrosia trifida pollen (20000 [PNU]/1mL)	Injection, solution	Subcutaneous	ALK-Abello, Inc.	1965-01-01	Not applicable
Mixed Ragweed	Ambrosia artemisiifolia pollen (20000 [PNU]/1mL) + Ambrosia trifida pollen (20000 [PNU]/1mL)	Injection, solution	Subcutaneous	ALK-Abello, Inc.	1975-01-15	Not applicable
Mixed Ragweed	Ambrosia artemisiifolia pollen (10000 [PNU]/1mL) + Ambrosia trifida pollen (10000 [PNU]/1mL)	Injection, solution	Subcutaneous	ALK-Abello, Inc.	1965-01-01	2023-05-19
Mixed Ragweed	Ambrosia artemisiifolia pollen (0.1 g/1mL) + Ambrosia trifida pollen (0.1 g/1mL)	Injection, solution	Subcutaneous	ALK-Abello, Inc.	1965-01-01	Not applicable
Mixed Ragweed	Ambrosia artemisiifolia pollen (10000 [PNU]/1mL) + Ambrosia trifida pollen (10000 [PNU]/1mL)	Injection, solution	Subcutaneous	ALK-Abello, Inc.	1975-01-15	Not applicable
Mixed Ragweed	Ambrosia artemisiifolia pollen (0.05 g/1mL) + Ambrosia trifida pollen (0.05 g/1mL)	Injection, solution	Percutaneous	ALK-Abello, Inc.	1998-02-23	Not applicable
Mixed Ragweed	Ambrosia artemisiifolia pollen (40000 [PNU]/1mL) + Ambrosia trifida pollen (40000 [PNU]/1mL)	Injection, solution	Subcutaneous	ALK-Abello, Inc.	1965-01-01	Not applicable
National Weed Mix	Ambrosia artemisiifolia pollen (0.02 g/1mL) + Amaranthus retroflexus pollen (0.02 g/1mL) + Ambrosia trifida pollen (0.02 g/1mL) + Chenopodium album pollen (0.02 g/1mL) + Xanthium strumarium pollen (0.02 g/1mL)	Solution	Intradermal; Percutaneous; Subcutaneous	Greer Laboratories, Inc.	1981-09-15	Not applicable

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
Allergen Pack Gs Ragweed Mix	Ambrosia artemisiifolia pollen (1 g/20mL) + Sodium chloride (0.9 g/1mL)	Kit	Intradermal; Subcutaneous	Alvix Laboratories	2015-07-09	2018-03-08

Categories

Drug Categories

• Allergenic Extracts
• Cell-mediated Immunity
• Increased Histamine Release
• Increased IgG Production
• Standardized Pollen Allergenic Extract

Classification

Not classified

Affected organisms

Not Available

Chemical Identifiers

UNII

9W34L2CQ9A

CAS number

Not Available

References

General References

1. DailyMed Label: RAGWITEK (Short Ragweed Pollen Allergen Extract) Tablet for Sublingual Use [Link]
2. DailyMed Label: SHORT RAGWEED (ambrosia artemisiifolia) injection for cutaneous, subcutaneous, or intradermal use [Link]

External Links

PubChem Substance

347910560

RxNav

1347557

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Injection, solution	Percutaneous; Subcutaneous
Kit	Intradermal; Subcutaneous
Injection, solution	Subcutaneous	0.05 g/1mL
Injection, solution	Subcutaneous	0.10 g/1mL
Injection, solution	Subcutaneous	20000 [PNU]/1mL
Injection, solution	Subcutaneous	40000 [PNU]/1mL
Injection, suspension	Subcutaneous	10000 [PNU]/1mL
Injection, suspension	Subcutaneous	20000 [PNU]/1mL
Tablet, orally disintegrating	Sublingual
Injection, solution	Percutaneous
Injection, solution	Subcutaneous
Solution	Intradermal; Percutaneous; Subcutaneous
Injection, solution	Intradermal	500 [PNU]/1mL
Injection, solution	Percutaneous; Subcutaneous	0.05 g/1mL
Injection, solution	Intradermal
Tablet	Sublingual	12 [Amb'a'1'U]/1
Tablet, orally disintegrating	Sublingual	12 unit
Powder	Oral	12 SQ-Amb
Injection	Cutaneous; Intradermal; Subcutaneous	1 g/10mL
Injection, solution	Percutaneous	0.05 g/1mL
Injection, solution	Intradermal; Subcutaneous	0.05 g/1mL
Injection, solution	Intradermal; Subcutaneous	0.1 g/1mL
Injection, solution	Intradermal; Subcutaneous	20000 [PNU]/1mL
Injection, solution	Intradermal; Subcutaneous	40000 [PNU]/1mL
Solution	Intradermal; Percutaneous; Subcutaneous	0.05 g/1mL
Injection, solution	Intradermal; Subcutaneous	100000 [AU]/1mL
Injection, solution	Percutaneous; Subcutaneous	1 g/10mL
Injection, solution	Intradermal; Subcutaneous

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

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Drug created at December 01, 2015 20:03 / Updated at June 03, 2022 07:24