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Displaying results 181 - 190 of 144679 in total
  1. Drug

    Oxybuprocaine

    go.drugbank.com/drugs/DB00892
    ApprovedInvestigational

    Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. … Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.

    Salts: Oxybuprocaine hydrochlorideMixtures: Fluorescein Sodium and Benoxinate Hydrochloride, Fluorescein Sodium and Benoxinate Hydrochloride
  2. Drug

    Tiagabine

    go.drugbank.com/drugs/DB00906
    Approved

    Tiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants.

    Salts: Tiagabine hydrochlorideCategories: Nipecotic Acid and Derivatives
  3. Drug

    Ondansetron

    go.drugbank.com/drugs/DB00904
    ApprovedInvestigationalWithdrawn

    [L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation. … It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

    Salts: Ondansetron hydrochloride, Ondansetron hydrochloride dihydrateCategories: Antiemetics and Antinauseants
  4. Drug

    STRO-001

    go.drugbank.com/drugs/DB17224
    Investigational

    Synonyms: antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable maytansinoid linker warheads
  5. Drug

    Triprolidine

    go.drugbank.com/drugs/DB00427
    Approved

    First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.

    Salts: Triprolidine hydrochloride, Triprolidine hydrochloride monohydrateMixtures: A-FERIN SINUS 500/30/1.25 MG FİLM KAPLI TABLET, 20 ADET, PEACEF SYRUP 30 mg/5 ml
  6. Drug

    Esmolol

    go.drugbank.com/drugs/DB00187
    ApprovedInvestigationalWithdrawn

    The FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride that supply 250 milligrams/milliliter of concentrated esmolol per 10-milliliter ampule … Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine.

    Salts: Esmolol hydrochlorideProducts: Esmolol Hydrochloride, Esmolol Hydrochloride in Water
  7. Drug

    Surovatamig

    go.drugbank.com/drugs/DB19420
    Investigational

    TNB-486 is under investigation in clinical trial NCT06564038 (A Study of AZD0486 Monotherapy or in Combination With Other Anti-cancer Agents for Mature B-cell Malignancies).

    Synonyms: sapiens and humanized monoclonal antibody asymetric,, immunoglobulin (H-gamma4_L-kappa)_VH-G4(h-CH2-CH3), anti-[Homo sapiens CD3D (CD3 delta) and CD3E (CD3 epsilon, Leu-4) dimer] and anti-[Homo sapiens CD19 (B lymphocyte surface antigen B4, Leu-12)], Homo
  8. Drug

    Cefepime

    go.drugbank.com/drugs/DB01413
    ApprovedInvestigational

    Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics. … [A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical

    Salts: Cefepime hydrochlorideCategories: cefepime and amikacin
  9. Drug

    Benzocaine

    go.drugbank.com/drugs/DB01086
    ApprovedInvestigational

    Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.

    Salts: Benzocaine hydrochlorideMixtures: Ndc 72934- 5010-4 Benzocaine 20% / Lidocaine 8% / Tetracaine 4%., Benzocaine 20% / Lidocaine 10% / Tetracaine 10%
  10. Drug

    Ginsenoside Rd

    go.drugbank.com/drugs/DB19256
    Investigational

    Ginsenoside Rd is under investigation in clinical trial NCT00815763 (Efficacy and Safety of Ginsenoside-rd for Acute Ischemic Stroke).

    Synonyms: Ginsenoside Rd (constituent of american ginseng, asian ginseng, and tienchi ginseng), .)-20-(.beta.-d-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-o-.beta.-d-glucopyranosyl-