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Displaying results 181 - 190 of 144705 in total
  1. Drug

    Vudalimab

    go.drugbank.com/drugs/DB18833
    Investigational

    Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate Cancer).

    Synonyms: Immunoglobulin half-ig g1-kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and anti-(homo sapienspdcd1 (programmed cell death 1, pd-1, pd1, cd279)),
  2. Drug

    Zinc oxide

    go.drugbank.com/drugs/DB09321
    ApprovedInvestigational

    It occurs naturally as the mineral zincite, but most zinc oxide is produced synthetically. … It is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments

    Mixtures: May Newyork Super Sun 10g, Dr Frog Pp Sun BlockCategories: Basic Powders and Demulcents, Basic Ointments and Protectants
  3. Drug

    Diphenhydramine

    go.drugbank.com/drugs/DB01075
    ApprovedInvestigational

    stings, and rashes [L5263, L5266, L5269, F3379]. … While its use in allergy therapy can sometimes fall out of favor due to its sedative effect, diphenhydramine has been repurposed for use within many non-prescription over-the-counter sleep aids and cough-and-cold

    Mixtures: Acetaminophen 500mg Diphenhydramine HCl 25mg, Benadryl Bug Bite ReliefCategories: Hypnotics and Sedatives, naproxen and diphenhydramine
  4. Drug

    Ubidecarenone

    go.drugbank.com/drugs/DB09270
    ApprovedInvestigationalNutraceutical

    From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. … [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant to treat, cure or prevent any disease.

    Mixtures: Co-q10 M.R.B. 100mg and Vitamin E, Folic-KCategories: Enzymes and Coenzymes, Diet, Food, and Nutrition
  5. Drug

    Doxepin

    go.drugbank.com/drugs/DB01142
    ApprovedInvestigational

    [L5977] Doxepin was developed by Pfizer and FDA approved in 1969 as an antidepressant.[L5971] However, in 2010 it was approved for the treatment of insomnia. … Doxepin is a psychotropic agent with antidepressant and anxiolytic properties.

    Categories: Hypnotics and Sedatives, Antipruritics and Local AnestheticsProducts: DONEURIN 25MG, Triadapin Cap 25mg
  6. Drug

    Atomoxetine

    go.drugbank.com/drugs/DB00289
    ApprovedInvestigational

    [A178090] Atomoxetine has been shown to specifically increase NA and DA within the prefrontal cortex, but not in the nucleus accumbens (NA) or striatum. … [L6037] However, these stimulant medications are limited by dose-related side effects and concerns of abuse.

    Categories: Psychostimulants, Agents Used for ADHD and NootropicsProducts: AGAKALIN 25MG FILMTAB, ATOMOXETIN BETA 25MG
  7. Drug

    Epirubicin

    go.drugbank.com/drugs/DB00445
    ApprovedInvestigational

    An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.

    Categories: Anthracyclines and Related Substances, Antineoplastic and Immunomodulating AgentsProducts: PHARMORUBICIN CS 20MG/10ML, PHARMORUBICIN CS 50MG/25ML
  8. Drug

    Telitacicept

    go.drugbank.com/drugs/DB18312
    Investigational

    Synonyms: (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY PROTEIN TNFRSF13B) HUMAN EXTRACELLULAR DOMAIN FRAGMENT (13-118)-PEPTIDECategories: Amino Acids, Peptides, and Proteins
  9. Drug

    Zuclopenthixol

    go.drugbank.com/drugs/DB01624
    ApprovedInvestigational

    These are organic polycyclic compounds containing a thioxanthene moiety, which is an aromatic tricycle derived from xanthene by replacing the oxygen atom with a sulfur atom. … It is known that zuclopenthixol is metabolized by Cytochrome P450 2D6. Zuclopenthixol was approved for use in Canada in 2011, but is not approved for use in the United States.

    Products: CIATYL Z 10MG, CLOPIXOL 10MG
  10. Drug

    Propranolol

    go.drugbank.com/drugs/DB00571
    ApprovedInvestigational

    [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904]

    Mixtures: Propranolol Hydrochloride and Hydrochlorothiazide, Propranolol Hydrochloride and HydrochlorothiazideCategories: propranolol and thiazides, Beta Blocking Agents and Thiazides