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Coenzyme M
go.drugbank.com/drugs/DB09110ApprovedInvestigationalCoenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Products: Uromitexan Inj 100mg/ml, Uromes Injection 100mg/mlBromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigationalBromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducin...
Products: TP-BROMPIRIN 40MG/ML SOLUTION, BUCOLYN 20MG/G POWDERSecukinumab
go.drugbank.com/drugs/DB09029ApprovedInvestigational[A249840] Following its first global approval in Japan in December 2014, secukinumab was approved by the European Commission on January 15, 2015, and by the FDA a few days after (January 21, 2015). … [L39600] By blocking the actions of IL-17A, secukinumab works to inhibit the pro-inflammatory pathways that drive immune-mediated inflammatory disorders.
Products: COSENTYX SOLUTION FOR INJECTION IN PREFILLED SYRINGE 300MG/2ML, Fraizeron 300mg/2ml solution for injection in pre-filled penPioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigational[L11416] The thiazolidinedione class of medications, which also includes [rosiglitazone] and [troglitazone], exerts its pharmacological effect primarily by promoting insulin sensitivity and the improved
Mixtures: OSENI FILM COATED TABLET 25MG/ 30MG, OSENI FILM COATED TABLET 12.5MG/ 30MGProducts: ACTOS 30MG TABLET, PIOLET 30MG TABLETSHaloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigationalhaloperidol to lower-potency first-generation antipsychotics such as [DB00477], [DB01624], [DB00623], and [DB01403], haloperidol typically demonstrates the least amount of side effects within this class, but … be caused by a hyperdopaminergic state within the limbic system of the brain.
Products: HALDOL JANSSEN 10MG, Haloperidol-10 Tab 10mgOcrelizumab
go.drugbank.com/drugs/DB11988ApprovedInvestigationalDeveloped by Genentech/Roche, ocrelizumab was approved by the FDA in March 2017 under the market name Ocrevus for intravenous injection. … [L1199] Most patients with MS experience episodes of relapses with worsening function, followed by recovery periods or remissions.
Products: OCREVUS 300mg/10mL Concentrate for Solution for Infusion, OCREVUS® CONCENTRADO PARA SOLUCION PARA INFUSION 300MG/10MLDigoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigational[A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. … [L9143] This drug originates from the foxglove plant, also known as the _Digitalis_ plant[T610], studied by William Withering, an English physician and botanist in the 1780s.
Products: Digoxin Injection C.S.D., Pediatric Digoxin Injection C.S.D.Adenosine
go.drugbank.com/drugs/DB00640ApprovedInvestigational[A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole]
Mixtures: Lebody Bu W Renewal Up, MIRACLETOX Time Rewind Advanced Lifting Ampoule 40mLProducts: ADOZIN 50MG/10ML IV ENJEKSIYON VE INFÜZYON IÇIN ÇÖZELTI IÇEREN FLAKON, 10 FLAKON, ADOZIN 10MG/2ML IV ENJEKSIYON VE INFÜZYON IÇIN ÇÖZELTI IÇEREN AMPUL, 10 AMPULEpcoritamab
go.drugbank.com/drugs/DB16672ApprovedInvestigationalIn May 2023, epcoritamab was approved by the FDA under accelerated approval for the treatment of relapsed or refractory DLBCL. … [A259736,A258488,A259761,L46516] Epcoritamab promotes the activation and expansion of T-cells and, by being able to bind to both CD20 and CD3, it leads to the T-cell–mediated killing of CD20+ malignant
Products: Epkinly Solution for Injection 4mg/0.8ml, Epkinly Solution for Injection 48mg/0.8mlMethotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigational[A180322] Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and non-Hodgkin's lymphoma
Products: TREXJECT 10MG (10MG/ML), METEX FS 10MG (50MG/ML)