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Pergolide
go.drugbank.com/drugs/DB01186ApprovedVet approvedWithdrawnThe drug was withdrawn from the US market in March 2007 and from the Canadian market in August 2007. … It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian syndrome. It was later found that pergolide increased the risk of cardiac valvulopathy.
Sodium tartrate
go.drugbank.com/drugs/DB13707ApprovedWithdrawnIt is obtained as a byproduct of wine manufacturing. Sodium tartrate is generally recognized as safe (GRAS) as a direct human food ingredient. … It acts as an emulsifier and pH control agent in food products [L2590].
Meradimate
go.drugbank.com/drugs/DB11096ApprovedMeradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. … [T200] It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products.
Isopropyl myristate
go.drugbank.com/drugs/DB13966ApprovedIsopropyl myristate has been largely studied and impulsed as a skin penetration enhancer. … [A178078] At the moment the primary usage for which isopropyl myristate is formally indicated is as the active ingredient in a non-prescription pediculicide rinse [A32333, L1964, L1966].
Phenmetrazine
go.drugbank.com/drugs/DB00830ApprovedIllicitA sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine.
Dimethicone 410
go.drugbank.com/drugs/DB14005Approved[L1769] It is currently recognized by the FDA as a skin protectant OTC ingredient for human use in a concentration of 1-30%. … [L2162] The name dimethicone has a lot of nomenclature inconsistencies as it is used to refer to common names, generic names, trade names or even for the listing of mixtures.
Periciazine
go.drugbank.com/drugs/DB01608ApprovedIt is used as an adjunctive medication in some psychotic patients, for the control of residual prevailing hostility, impulsiveness and aggressiveness. … Pericyazine, like other phenothiazines, is presumed to act principally in the subcortical areas, by producing what has been described as a central adrenergic blockade.
Oxymetholone
go.drugbank.com/drugs/DB06412ApprovedIllicitAnabolic-androgenic steroids (AAS), such as oxymetholone, have been abused by bodybuilders and athletes. … Oxymetholone is a synthetic anabolic steroid marketed under the brand name Anapolon by Hoffmann La Roche Limitedand used in the treatment of osteoporosis, anaemia, and as an agent to stimulate muscle growth
Castor oil
go.drugbank.com/drugs/DB11113ApprovedNutraceuticalVet approvedIt can also be found in hard candies as a release agent and anti-sticking agent, or supplementary vitamins and mineral oral tablets as an ingredient for protective coatings. … Castor oil is found in over-the-counter oral liquids as a stimulant laxative, and is also added in commercial cosmetic, hair, and skincare products.
Enzacamene
go.drugbank.com/drugs/DB11219ApprovedIt is used in cosmetic products such as sunscreen to provide skin protection against UV rays. … Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter.