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Ceftaroline fosamil
go.drugbank.com/drugs/DB06590ApprovedInvestigationalCeftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and skin structure infections
Categories: Heterocyclic Compounds, 2-RingSynonyms: (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylateLazertinib
go.drugbank.com/drugs/DB16216ApprovedInvestigationalLazertinib is an oral, third-generation, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). Lazertinib was first approved in South Korea on January 18, 2021, for the treatment of EGFR T790M mutation-positive non-sma...
Synonyms: 2-PROPENAMIDE, N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)-2-PYRIMIDINYL)AMINO)-4-METHOXY-2-(4-MORPHOLINYL)PHENYL)-, N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YL)AMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDECategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide
go.drugbank.com/drugs/DB07632ExperimentalSynonyms: 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide5-[2-(TRIFLUOROMETHYL)PHENYL]-2-FUROIC ACID
go.drugbank.com/drugs/DB07759ExperimentalSynonyms: 5-[2-(TRIFLUOROMETHYL)PHENYL]-2-FUROIC ACIDUridine-5'-diphosphate-2-deoxy-2-fluorogalactose
go.drugbank.com/drugs/DB02976ExperimentalSynonyms: Uridine-5'-diphosphate-2-deoxy-2-fluorogalactoseOxitriptan
go.drugbank.com/drugs/DB02959ApprovedInvestigationalNutraceuticalWithdrawn5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in … Several double-blind placebo-controlled clinical trials have demonstrated the effectiveness of 5-HTP in the treatment of depression, though a lack of high quality studies has been noted.
Synonyms: L-5-HTP, 5-hydroxy-L-tryptophanIndigotindisulfonic acid
go.drugbank.com/drugs/DB11577ApprovedInvestigational[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. … Indigotindisulfonic acid is a blue-colored dye with a variety of uses.
Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingSynonyms: 2-(1,3-Dihydro-3-oxo-5-sulpho-2H-indol-2-ylidene)-3-oxoindoline-5-sulphonic acid, FD&C Blue #2Ceforanide
go.drugbank.com/drugs/DB00923ApprovedIt has a longer elimination half-life than any currently available cephalosporin.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (6R,7R)-7-[[2-[2-(aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7β-[2-(aminomethyl)phenyl]acetamido-3-{[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl-3,4-didehydrocepham-4-carboxylic acidAmobarbital
go.drugbank.com/drugs/DB01351ApprovedIllicitA barbiturate with hypnotic and sedative properties (but not antianxiety). … Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Synonyms: 5-ethyl-5-(3-methylbutyl)barbituric acid, 5-ethyl-5-(3-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrioneCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersCefamandole
go.drugbank.com/drugs/DB01326ApprovedWithdrawnIt is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, [cefamandole nafate]. It is no longer marketed in the United States.
Synonyms: L-Cefamandole, 7-D-MANDELAMIDO-3-(((1-METHYL-1H-TETRAZOL-5-YL)THIO)METHYL)-3-CEPHEM-4-CARBOXYLIC ACIDCategories: Heterocyclic Compounds, 2-Ring