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Omalizumab
go.drugbank.com/drugs/DB00043ApprovedInvestigational[L50482] IgE promotes the release of inflammatory mediators from mast cells and basophils during allergic and inflammatory reactions. … [L50482] It is used to treat a range of immune and inflammatory conditions, including allergies, urticaria, and asthma.[A263507]
Products: XOLAIR ® 150 MG, XOLAIR 150 MG ENJEKSIYONLUK COZELTI İÇİN TOZ İÇEREN FLAKON, 1 ADETAvapritinib
go.drugbank.com/drugs/DB15233ApprovedInvestigationalAvapritinib, or BLU-285,[A189327] is a selective tyrosine kinase inhibitor of KIT and platelet derived growth factor receptor alpha indicated for the treatment of unresectable, metastatic gastrointestinal … Avapritinib was granted FDA approval on 9 January 2020 [L40363] and EMA approval on 24 September 2020.[L41464]
Vinflunine
go.drugbank.com/drugs/DB11641ApprovedInvestigationalEfficacy and safety of vinflunine has not been studied in patients with performance status of 2 or less. … Having an incidence of 429,700 new cases per year worldwide, urothelial carcinoma of the bladder is one of the most common malignancies that mostly affects individuals aged 50–79 years [A32626].
Products: Javlor Concentrate for Solution for Infusion 25 mg/mLBrilliant green cation
go.drugbank.com/drugs/DB11279ApprovedVet approvedBrilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to color silk and wool.
Categories: Compounds used in a research, industrial, or household settingPromazine
go.drugbank.com/drugs/DB00420ApprovedVet approvedWithdrawnIt is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: PROMAZINA EGDiethylcarbamazine
go.drugbank.com/drugs/DB00711ApprovedInvestigationalVet approvedWithdrawnAn anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Clomifene
go.drugbank.com/drugs/DB00882ApprovedInvestigationalA triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Categories: Sex Hormones and Modulators of the Genital SystemProducts: DUINUM TABLET 50 mg, KLOMEN 50 MG, 30 ADETBamlanivimab
go.drugbank.com/drugs/DB15718ApprovedInvestigationalBamlanivimab consists of two identical light chains of 214 amino acids and two identical heavy chains of 455 amino acids each; the Fc region is unmodified. … [L20979] Based on phase 2 clinical trial (BLAZE-1) interim results, bamlanivimab was granted Emergency Use Authorization (EUA) by the FDA on November 10, 2020.
Lithium carbonate
go.drugbank.com/drugs/DB14509ApprovedInvestigationalThough it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: ACTIBUTIN 300 MG, THERALITE® 300 MGLiraglutide
go.drugbank.com/drugs/DB06655ApprovedInvestigational[A6932] Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer on the remaining lysine residue at position 26 of the peptide precursor. … [A6932] Liraglutide was granted FDA approval on January 25, 2010.[L6070]
Products: SAXENDA® 6 MG/ML, SAXENDA 6 MG/ML ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM, 1 ENJEKTÖR