Search

Displaying results 1891 - 1900 of 8411 in total
  1. Drug

    Thalidomide

    go.drugbank.com/drugs/DB01041
    ApprovedInvestigationalWithdrawn

    A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects. … Due to severe teratogenicity, pregnancy must be excluded before the start of treatment and patients must enrol in the THALIDOMID Risk Evaluation and Mitigation Strategy (REMS) program to ensure contraception

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersInternational brands: Pro-ban M
  2. Drug

    Frespaciguat

    go.drugbank.com/drugs/DB21683
    Investigational

    PH-COPD). … Frespaciguat has a monoisotopic molecular weight of 608.14 Da.

  3. Drug

    Curcuma aromatica root oil

    go.drugbank.com/drugs/DB11301
    Approved

    The major constituents of Curcuma aromatica root oil are reported to be camphor, curzerenone, α-turmerone, ar-turmerone and 1,8-cineole [A27219].

  4. Drug

    Cisatracurium

    go.drugbank.com/drugs/DB00565
    ApprovedInvestigational

    [A243416,A253592] Cisatracurium is an R-cis-R-cis isomer of [atracurium] and has approximately 3 times its neuromuscular blocking potency. … [A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597].

  5. Drug

    Attapulgite

    go.drugbank.com/drugs/DB01574
    ApprovedVet approvedWithdrawn

    Attapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract...

    Mixtures: Donnagel-PG Cap
  6. Drug

    Revefenacin

    go.drugbank.com/drugs/DB11855
    ApprovedInvestigational

    Revefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting muscarinic antagonists (LAMA). The labile primary amide in the structure produces a "soft-drug" site that allows rapid systemic ...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  7. Drug

    Doxercalciferol

    go.drugbank.com/drugs/DB06410
    ApprovedInvestigational

    D2. … Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin

    Categories: Vitamin D and AnaloguesSynonyms: 1-Hydroxyvitamin D2, 1α-hydroxyvitamin D2
  8. Drug

    Chimeric antigen receptor T-cells

    go.drugbank.com/drugs/DB22146
    Investigational

    Chimeric Antigen Receptor T-cells is under investigation in clinical trial NCT05225363 (Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian

    Synonyms: CAR T, CAR - T
  9. Drug

    Zafirlukast

    go.drugbank.com/drugs/DB00549
    Approved

    Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  10. Drug

    Selamectin

    go.drugbank.com/drugs/DB11459
    ExperimentalVet approved

    as prevent heartworms, fleas, ear mites, hookworms, and roundworms in cats. … Selamectin is a topical parasiticide and antihelminthic used on dogs and cats to treat and prevent infections of heartworms, fleas, ear mites, sarcoptic mange, and certain types of ticks in dogs as well

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates