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Displaying results 1891 - 1900 of 2454 in total

Drug
Polyethylene glycol 300
go.drugbank.com/drugs/DB11161
Approved
Polyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 g/mol. It is a clear viscous liquid at room temperature with non-volatile, stable properties . Polyethylene glycols are widely used i...
Categories: P-glycoprotein inhibitors
Drug
Polysorbate 20
go.drugbank.com/drugs/DB11178
Approved
Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is a wetting agent in fo...
Categories: P-glycoprotein inhibitors
Drug
Tetrofosmin
go.drugbank.com/drugs/DB11180
Approved
Tetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds. It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of ...
Categories: P-glycoprotein substrates
Drug
Poloxamer 407
go.drugbank.com/drugs/DB11252
Investigational
Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks, both hydrophilic in nature. P...
Categories: P-glycoprotein inhibitors
Drug
Prothrombin
go.drugbank.com/drugs/DB11311
ApprovedInvestigational
Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with acute major bleeding.
Mixtures: Beriplex P/n 500, Beriplex P/n 1000
Drug
Nonivamide
go.drugbank.com/drugs/DB11324
Approved
The structures of [DB06774] and nonivamide differ only slightly with respect to the fatty acid moiety of the side chain (8-methyl nonenoic acid versus nonanoic acid) [F31].
Drug
Poloxamer 188
go.drugbank.com/drugs/DB11333
Approved
Poloxamer 188 (P188) is a nonionic block linear copolymer that exhibits rheologic, anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models . Composed of two hydrophilic side-chains attached to a ...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inhibitors
Drug
Chloroform
go.drugbank.com/drugs/DB11387
ApprovedVet approvedWithdrawn
Chloroform is an organic small molecule, member of the family of the chloromethanes that presents a formula of CHCl3. It is a colorless, sweet-smelling, dense liquid that is produced on a large scale as a precursor to PTFE and refrigeran...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Substrates
Drug
Enrofloxacin
go.drugbank.com/drugs/DB11404
InvestigationalVet approved
Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant strains of Campylob...
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 Inhibitors
Drug
Fenbendazole
go.drugbank.com/drugs/DB11410
InvestigationalVet approved
Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, ae...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Substrates