Prothrombin is a coagulation factor used for emergency reversal of vitamin K antagonist therapy. A medication used to reverse the effects of certain blood thinners in emergencies.
- Mechanism
- Curator reviewed
Pharmacologically active on Prothrombin, Fibrinogen alpha chain, and Fibrinogen beta chain
- Primary indication
- Prothrombin is administered as part of a cocktail containing several coagulation factors.Curator reviewed · 2 structured indications
- First approval
- Canada, 2007 · United States, 2013
- Also known as
- Coagulation factor II (human) · Coagulation factor II human · Factor II · Factor II (prothrombin) · Human coagulation factor II
- Brand names
Resolves to
Compound
Clinical / RWD
What you can answer from here — as of June 15, 2026
5Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Prothrombin, and which of those have an active Phase 3 trial?
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