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Hyoscyamine
go.drugbank.com/drugs/DB00424ApprovedInvestigational[A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties. … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family.
Mixtures: Urin D/S, Uretron D/SSynonyms: [3(S)-endo]-α-(hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (S)-atropine1D09C3
go.drugbank.com/drugs/DB05121Experimentalclass II-positive tumor cells, which include those in B-cell and T-cell lymphomas. 1D09C3 has been shown to induce programmed cell death and does not require a functioning immune system for its cell-killing … 1D09C3, a monoclonal antibody against lymphoid cancers, is an anti-MHC (major histocompatibility complex) class II monoclonal antibody.
Sofosbuvir
go.drugbank.com/drugs/DB08934ApprovedInvestigationalSince 2014, sofosbuvir has been available as a fixed dose combination product with [DB09027] (tradename Harvoni) used for the treatment of chronic Hepatitis C. … When combined together, ledipasvir and sofosbuvir as the combination product Harvoni has been shown to achieve a SVR between 93 and 99% after 12 weeks of treatment [A7535].
Synonyms: S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)- (phenoxy)phosphorylamino)propanoateMixtures: HARVONI®, EPCLUSA®Phenindione
go.drugbank.com/drugs/DB00498ApprovedInvestigationalAn indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects.
Synonyms: 2-Phenyl-1,3-indandione, 2-phenyl-1,3-diketohydrindeneCategories: Vitamin K AntagonistsChlorphentermine
go.drugbank.com/drugs/DB01556ApprovedIllicitWithdrawnA sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension.
Synonyms: 4-Chloro-a,a-dimethylbenzeneethanamine, 4-Chloro-a,a-dimethylphenethylamineHydroxocobalamin
go.drugbank.com/drugs/DB00200ApprovedInvestigationalHydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency.
Mixtures: TRIBEDOCE C/L, ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL (5+5)Categories: Vitamin B Complex, Heterocyclic Compounds, 1-RingMethyltestosterone
go.drugbank.com/drugs/DB06710ApprovedInvestigationalAlso, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US. … A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies.
Categories: 3-Oxoandrosten (4) Derivatives, Cytochrome P-450 SubstratesSynonyms: 17-beta-Hydroxy-17-methylandrost-4-en-3-one, 17alpha-Methyl-3-oxo-4-androsten-17beta-olPinacidil
go.drugbank.com/drugs/DB06762ApprovedThis drug has been discontinued by the FDA. … Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesChlorpheniramine
go.drugbank.com/drugs/DB01114ApprovedInvestigationalA histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications.
Mixtures: L M 6, K-Y-6Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingCholecalciferol
go.drugbank.com/drugs/DB00169ApprovedInvestigationalNutraceuticalVitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689]. … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation
Synonyms: Vitamin D 3, Vitamin D-3International brands: Delta-D, Micro-D