Chlorphentermine

DB01556ApprovedIllicitWithdrawnSmall molecule

A sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension. (From... (From Martindale, The Extra Pharmacopoeia, 30th ed, p1223).

Mechanism: Pharmacologically active on Sodium-dependent serotonin transporter
Curator reviewed
Primary indication: Used as an appetite suppressant.Curator reviewed
Formula / weight: C₁₀H₁₄ClN · 183.678 g/mol (avg)

Resolves to

Compound

UNIINHW07912O7CAS461-78-9ChEMBLCHEMBL1201269ChEBI3646PubChem10007KEGGC07559

Structure

InChIKeyZCKAMNXUHHNZLN-UHFFFAOYSA-NSMILESCC(C)(N)CC1=CC=C(Cl)C=C1

Targets

P31645SLC6A4

What you can answer from here — as of September 11, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1,019Drug interactionsStructured to mechanism, not free text

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Chlorphentermine, and which of those have an active Phase 3 trial?

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