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Displaying results 1901 - 1910 of 5758 in total
  1. Drug

    Denosumab

    go.drugbank.com/drugs/DB06643
    ApprovedInvestigational

    Jubbonti® (denosumab-bbdz)[L53058]—were approved by the FDA in March 2024 for all indications of the reference products Xgeva® and Prolia®; Both biosimilars also received marketing authorization in the EU

  2. Drug

    Azilsartan medoxomil

    go.drugbank.com/drugs/DB08822
    ApprovedInvestigational

    Although there is no clinical significance yet determined, azilsartan medoxomil may have potential off-label uses in patients with a history of myocardial infarction or heart failure.[A232863]

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  3. Drug

    Cethromycin

    go.drugbank.com/drugs/DB06419
    Investigational

    Cethromycin is a 3-keto (ketolide) derivative of erythromycin A with an 11,12-carbamate group and an O-6-linked aromatic ring system. Cethromycin represents a joint development effort by Abbott Laboratories, Taisho Pharmaceuticals, and A...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  4. Drug

    Zinc glycinate

    go.drugbank.com/drugs/DB14493
    Investigational

    Glycoprotein marker of gastrointestinal cancer.

    Mixtures: FeRiva 21-7 28-Day
  5. Drug

    Ethylmorphine

    go.drugbank.com/drugs/DB01466
    IllicitInvestigational

    It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  6. Drug

    Difluocortolone

    go.drugbank.com/drugs/DB09095
    ApprovedWithdrawn

    It was submitted to the FDA in July 1984 by the pharmaceutical company Schering AG.[L1082]

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  7. Drug

    Ceramide NP

    go.drugbank.com/drugs/DB14111
    Investigational

    Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. … Ceramide 3 consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid) [A27233]. It is widely used as a moisturizer in various cosmetic and personal products.

    Synonyms: Ceramide NP, N-oleoylphytosphingosine
  8. Drug

    Norelgestromin

    go.drugbank.com/drugs/DB06713
    ApprovedInvestigational

    It is administered transdermally in combination with the estrogen [ethinyl estradiol], delivering both hormones systemically over a 7-day wear period.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Mirfentanil

    go.drugbank.com/drugs/DB09175
    Experimental

    Mirfentanil is a derivative of fentanyl that presents high selectivity for the mu opioid receptor.

  10. Drug

    Linifanib

    go.drugbank.com/drugs/DB06080
    Investigational

    Linifanib (ABT-869) is a small molecule vascular endothelial growth factor (VEGF) receptor-based kinase inhibitor that is designed to suppress tumor growth by preventing the formation of new blood vessels that supply the tumor with oxyge...

    Synonyms: N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N1-(2-fluoro-5-methylphenyl) urea, UREA, N-(4-(3-AMINO-1H-INDAZOL-4-YL)PHENYL)-N'-(2-FLUORO-5-METHYLPHENYL)-