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Phenindione
go.drugbank.com/drugs/DB00498ApprovedInvestigationalAn indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects.
Categories: Vitamin K AntagonistsSynonyms: 2-Phenyl-1,3-indandione, 2-phenyl-1,3-diketohydrindeneSimvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigationalwere found in clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while simvastatin has been found to have an average decrease in LDL-C of ~35%. … [A181087,A181553] Use of statins to target and reduce LDL levels has been shown in a number of landmark studies to significantly reduce the risk of development of CVD and all-cause mortality.
Synonyms: 2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-oneMixtures: TIAZOMET S®, TIAZOMET S®Cholecalciferol
go.drugbank.com/drugs/DB00169ApprovedInvestigationalNutraceuticalVitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689]. … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation
Synonyms: Vitamin D 3, Vitamin D-3International brands: Delta-D, Micro-DMagnesium
go.drugbank.com/drugs/DB14513ApprovedInvestigationalMagnesium is classified as an alkaline earth metal and has 2 hydration shells. … [A39559] Several factors and common behaviours reduce the availability of magnesium in the diet such as food processing and cooking vegetables (which are normally a rich source of magnesium).[A39559]
Mixtures: BLACKMORES teen multi for GUYS capsule, BLACKMORES teen multi for GIRLS capsuleProducts: MG 5 LONGORAL, MAGNEROT CLASSIC NCyclopentamine
go.drugbank.com/drugs/DB08999ApprovedWithdrawnIt has been widely discontinued due to the safety, effectiveness, and availability of a similar drug, propylhexedrine. … Cyclopentamine is a sympathomimetic alkylamine, classified as a vasoconstrictor. Cyclopentamine was an over the counter treatment for nasal congestion in Europe and Australia.
Cefmetazole
go.drugbank.com/drugs/DB00274ApprovedIt has a high rate of efficacy in many types of infection and to date no severe side effects have been noted. … A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidVilobelimab
go.drugbank.com/drugs/DB16416ApprovedInvestigationalVilobelimab is a chimeric monoclonal immunoglobulin G4 (IgG4) antibody that binds to the soluble form of human C5a with high affinity. … It consists of mouse anti-human complement factor 5a (C5a) monoclonal binding sites (variable regions of heavy and light chain regions) and human gamma 4 heavy chain and light kappa chain constant regions
Synonyms: IFX-1Zytron
go.drugbank.com/drugs/DB11768ApprovedWithdrawnDMPA has been investigated for the prevention, treatment, and basic science of Weight and Microbiota.
Synonyms: O-(2,4-dichlorophenyl)-O-methyl-isopropylphosphoramidothioateFluorometholone
go.drugbank.com/drugs/DB00324ApprovedInvestigationalA glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders.
Mixtures: FLU-SURE T® SUSPENSIÓN OFTÁLMICA, FML-SCategories: Corticosteroid Hormone Receptor Agonists, Cytochrome P-450 SubstratesLevamisole
go.drugbank.com/drugs/DB00848ApprovedInvestigationalVet approvedWithdrawn[A178123] Interestingly, levamisole has been found as an adulterant in cocaine and can lead to a variety of adverse effects in individuals using this drug.[A178120] … [A178117] This drug has also been used in combination with other drugs for the treatment of various cancers.
Categories: Heterocyclic Compounds, 1-RingProducts: PVP- LEVAMISOLE POUR-ON SOLUTION 20 %w/v, PARAKS 40 MG TABLET, 6 ADET