Search

Displaying results 1911 - 1920 of 3387 in total
  1. Drug

    Synthetic Conjugated Estrogens, A

    go.drugbank.com/drugs/DB09317
    Approved

    Synthetic conjugated estrogens A are composed of a blend of the following nine synthetic estrogenic substances: estrone sulfate, sodium equilin sulfate, sodium 17α-dihydroequilin sulfate, sodium 17α-estradiol sulfate, sodium 17β­ dihydro...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  2. Drug

    Norethynodrel

    go.drugbank.com/drugs/DB09371
    Approved

    A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it has usually been administered in combin...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  3. Drug

    Filapixant

    go.drugbank.com/drugs/DB21467
    Experimental

    Filapixant is a small molecule drug. The usage of the INN stem '-pixant' in the name indicates that Filapixant is a purinoreceptor (P2X) antagonist. Filapixant has a monoisotopic molecular weight of 521.17 Da.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  4. Drug

    Azamulin

    go.drugbank.com/drugs/DB20304
    Experimental

    Azamulin is a small molecule drug. Azamulin has a monoisotopic molecular weight of 478.26 Da.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Substrates
  5. Drug

    Burapitant

    go.drugbank.com/drugs/DB20607
    Experimental

    The usage of the INN stem '-pitant' in the name indicates that Burapitant is a neurokinin NK1​ (substance P) receptor antagonist. Burapitant has a monoisotopic molecular weight of 681.2 Da.

  6. Drug

    Floxuridine

    go.drugbank.com/drugs/DB00322
    ApprovedInvestigational

    An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous,...

    Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  7. Drug

    Trimethadione

    go.drugbank.com/drugs/DB00347
    ApprovedWithdrawn

    An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates
  8. Drug

    Nitisinone

    go.drugbank.com/drugs/DB00348
    Approved

    Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1 and Alkaptonuria. It is sold under the brand names Orfadin and Harliku.

    Synonyms: 2-(alpha,alpha,alpha-Trifluoro-2-nitro-p-tuluoyl)-1,3-cyclohexanedioneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Aminoglutethimide

    go.drugbank.com/drugs/DB00357
    ApprovedWithdrawn

    An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to estrogens. Aminoglutethimide has been used in the treatment of advanced...

    Synonyms: p-Aminoglutethimide, 2-(p-Aminophenyl)-2-ethylglutarimideCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP2C19 Inducers
  10. Drug

    Dydrogesterone

    go.drugbank.com/drugs/DB00378
    ApprovedInvestigationalWithdrawn

    A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates