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Displaying results 1921 - 1930 of 7063 in total
  1. Drug

    Pinoxepin

    go.drugbank.com/drugs/DB21397
    Experimental

    Pinoxepin is a small molecule drug. The usage of the INN stem '-oxepin' in the name indicates that Pinoxepin is a tricyclic compound. Pinoxepin has a monoisotopic molecular weight of 398.18 Da.

  2. Drug

    Ruzadolane

    go.drugbank.com/drugs/DB21444
    Experimental

    Ruzadolane is a small molecule drug. The usage of the INN stem '-adol/-adol-' in the name indicates that Ruzadolane is a analgesic. Ruzadolane has a monoisotopic molecular weight of 375.13 Da.

  3. Drug

    Letrozole

    go.drugbank.com/drugs/DB01006
    ApprovedInvestigational

    [A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623] … [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole], meaning it does not significantly affect cortisol, aldosterone, and thyroxine.

    Products: LETROZOL 1A PHARMA 2.5MG, LETROZOLO DOC GENERICI
  4. Drug

    Stem bromelain

    go.drugbank.com/drugs/DB12249
    Approved

    brand name Nexobrid [FDA Label]. … Bromelain itself belongs to a category of protein-digesting enzymes that are obtained commercially from the fruit or stem of pineapples [A27198].

  5. Drug

    Coal tar

    go.drugbank.com/drugs/DB11082
    Approved

    Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas.

    Mixtures: Medi-dan Shampoo, Targel SaProducts: Euro Oil, Euro Oil Forte
  6. Drug

    Erlotinib

    go.drugbank.com/drugs/DB00530
    ApprovedInvestigational

    Recent studies demonstrate that erlotinib is also a potent inhibitor of JAK2V617F, which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and a substantial proportion … Erlotinib binds to the epidermal growth factor receptor (EGFR) tyrosine kinase in a reversible fashion at the adenosine triphosphate (ATP) binding site of the receptor.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index
  7. Drug

    Tazemetostat

    go.drugbank.com/drugs/DB12887
    ApprovedInvestigational

    [A190363] Tazemetaostat was granted FDA approval on 23 January 2020.[L11476] … Tazemetostat is a methyltransferase inhibitor used to treat metastatic or locally advanced epithelioid sarcoma not eligible for complete resection.

  8. Drug

    Tea tree oil

    go.drugbank.com/drugs/DB11218
    ApprovedNutraceutical

    It has been a popular ingredient in a variety of household and cosmetic products due to its antiseptic, anti-inflammatory, broad-spectrum antimicrobial and antioxidant properties [A32438].

  9. Drug

    Tazobactam

    go.drugbank.com/drugs/DB01606
    ApprovedInvestigational

    Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved by the FDA in 2014[FDA label], providing wider antibacterial coverage for gram-negative infections … It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections.

    Mixtures: KABICTAM® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE, PIPERACILINA 4G + TAZOBACTAM 0.5G POLVO ESTERIL PARA RECONSTITUIR A SOLUCION INYECTABLE
  10. Drug

    Venetoclax

    go.drugbank.com/drugs/DB11581
    ApprovedInvestigational

    Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. … prior therapy [FDA label].

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index