Explore a selection of our essential drug information below, or:
Identification
- Brand Names
- Cutar, Dhs Tar Shampoo, Psoriasin, Scytera, Tarsum, Tera Gel
- Generic Name
- Coal tar
- DrugBank Accession Number
- DB11082
- Background
Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds.
It has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea and eczema.
- Type
- Small Molecule
- Groups
- Approved
- Synonyms
- Coal tar
- Coal tars
- Tar, coal
Pharmacology
- Indication
Relieving itching, irritation, redness, dryness, scaling, and flaking of the skin caused by psoriasis, seborrhea, or eczema.
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Symptomatic treatment of Dandruff ••• ••• Used in combination to treat Psoriasis Combination Product in combination with: Salicylic acid (DB00936) ••• ••• ••••• Symptomatic treatment of Psoriasis ••• ••• Symptomatic treatment of Seborrheic dermatitis ••• ••• Used in combination for symptomatic treatment of Seborrhoeic dermatitis of the scalp Combination Product in combination with: Allantoin (DB11100) ••• ••• •••••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Decrease bacterial growth.
- Mechanism of action
Coal tar ointment is a keratolytic. It works by slowing bacterial growth and loosening and softening scales and crust.
- Absorption
Intended for local use only, no systemic absorption.
- Volume of distribution
Intended for local use only, no systemic absorption.
- Protein binding
Intended for local use only, no systemic absorption.
- Metabolism
Intended for local use only, no systemic absorption.
- Route of elimination
Intended for local use only, no systemic absorption.
- Half-life
Intended for local use only, no systemic absorption.
- Clearance
Intended for local use only, no systemic absorption.
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
LD50: Not available.
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- International/Other Brands
- Estar / Lavatar / Pixalbol
- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Advanced Psoriasis Therapy Soap 5 g/1000g Topical CVS Health 2016-06-10 Not applicable US 
Anti-Dandruff Shampoo 25 mg/1mL Topical Strategic Sourcing Services LLC 2005-05-21 Not applicable US Assured T And Plus Shampoo 5 mg/1mL Topical Bicooya Cosmetics Limited 2014-01-21 2020-04-04 US Balnetar Liq 2.5% Liquid 2.5 % Topical Westwood Squibb, Division Of Bristol Myers Squibb Canada Inc. 1963-12-31 2009-04-17 Canada 
Coal Tar Ointment 1.39 g/100mL Topical Nopsor USA Distribution Co., Inc. 2016-12-01 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Alphosyl Cream Coal tar (5.4 %) + Allantoin (2 %) Cream Topical Reed & Carnrick, Division Of Block Drug Company (Canada) Ltd. 1961-12-31 1999-07-05 Canada Alphosyl Lotion Coal tar (5 %) + Allantoin (2 %) Lotion Topical Reed & Carnrick, Division Of Block Drug Company (Canada) Ltd. 1958-12-31 1999-07-05 Canada Cera-Scalp Ointment Coal tar (12% w/w) + Octasulfur (4 % w/w) + Salicylic acid (2 % w/w) Ointment Topical HOE PHARMACEUTICALS SDN. BHD. 2020-09-08 Not applicable Malaysia 
Clobeta Coal tar (23 mg/1mL) + Clobetasol propionate (0.5 mg/1g) Kit Topical Tiber Laboratories, LLC 2011-04-06 2012-06-30 US Clobeta Coal tar (23 mg/1mL) + Clobetasol propionate (0.5 mg/1g) Kit Topical Tiber Laboratories, LLC 2011-04-06 2012-06-30 US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% Coal tar (8 g/100g) + Clobetasol propionate (0.05 g/100g) + Salicylic acid (6 g/100g) Cream Topical Sincerus Florida, LLC 2019-05-15 Not applicable US Pazol XS Coal tar (0.5 mg/1mL) + Octasulfur (20 mg/1mL) + Salicylic acid (20 mg/1mL) Shampoo Topical Stratus Pharmaceuticals 2011-07-01 2017-07-31 US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Humans and other mammals
Chemical Identifiers
- UNII
- R533ESO2EC
- CAS number
- 8007-45-2
- InChI Key
- Not Available
- InChI
- Not Available
- IUPAC Name
- Not Available
- SMILES
- Not Available
References
- General References
- External Links
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data4 Active Not Recruiting Basic Science Psoriasis / Psoriasis Vulgaris (Plaque Psoriasis) 1 somestatus stop reason just information to hide 4 Completed Basic Science General Anesthesia / Loss of Consciousness and Recovery of Consciousness / Propofol Pharmacodynamics / Propofol Plasma Concentration / Propofol Target Controlled Infusion 1 somestatus stop reason just information to hide 4 Unknown Status Treatment Atopic Dermatitis 1 somestatus stop reason just information to hide 3 Unknown Status Treatment Psoriasis 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Soap Topical 5 g/1000g Liquid Topical 2.5 % Ointment Topical Kit Topical Ointment Topical 1.39 g/100mL Shampoo Topical 5.39 g/250mL Liquid Topical 200 g / L Cream Topical 10 % v/w Cream Topical 15 % Cream Topical 5 % Solution Topical 200 mg / mL Ointment Topical 2 % w/w Lotion Topical 1.5 g/100mL Solution Topical 10 % w/v Soap Topical 21.3 mg/1g Soap Topical 2.13 g/100g Cream Topical Shampoo Topical 0.005 g/1g Shampoo Topical 0.5 % Solution Topical 2 % Gel Topical Lotion Topical 20 g/1000g Lotion Topical 8 g/1000g Cream Topical 20 g/1000g Cream Topical 10 % Gel Topical 5 % Cream Topical 2 g/100g Liquid Topical 2 % Liquid Topical 10 % Emulsion Topical 0.5 % Emulsion Topical 1 % Emulsion Unknown 1 % Emulsion Topical 2 % Shampoo, suspension Topical 0.65 % w/w Shampoo Topical 25 % v/v Solution Topical 20 % w/v Liquid; shampoo Topical 2 % Liquid Topical Solution Topical 10 % w/w Solution Topical 2 % w/w Emulsion Topical 4 g Cream Topical .55 g/100g Cream Topical 0.55 g/100g Soap Topical 0.5 % w/w Gel Topical 1.25 g / 100 g Ointment Topical 0.03 g/1g Gel Topical 0.02 g/1g Ointment Topical 0.02 g/1g Shampoo Topical 0.03 g/1g Shampoo Topical 1.1 % Liquid Topical 0.5 % Gel; shampoo Topical 2 % Gel Topical 1.5 % Shampoo Topical 10 mg/1mL Shampoo Topical 0.50 % Shampoo Topical 5 mg/1mL Shampoo Topical 2 % Solution Topical 20 % Lotion Topical 10 mg/1mL Shampoo Topical Shampoo Topical 1.77441 g/177.441mL Shampoo Topical 4.0 % Shampoo Topical 4.3 % Shampoo Topical 0.5 g/100mL Lotion / shampoo Topical Ointment Topical 5 % w/w Cream Topical 10 mg/1mL Cream Topical 5 mg/1mL Solution Topical 23 mg/1mL Liquid Topical 23 mg/1mL Ointment Topical 1 g/100mL Liquid Topical 6.6 mg/1mL Cream Topical 12.5 mg/1g Ointment Topical 20 mg/1g Gel Topical 1.25 % Gel Topical 12.5 mg/1g Lotion / shampoo Topical 20 mg/1g Solution Topical 0.66 % Ointment Topical 2.0 % Cream Topical 5 mg/1g Liquid Topical 0.66 % Cream Topical 1 g/100mL Cream Topical 2.0 % Ointment Topical 2.5 g/100g Ointment Topical 2 mg/100mL Aerosol, foam Topical 20 mg/1g Solution Topical Shampoo Topical 17 mg/1mL Lotion Topical 0.5 mg/1mL Emulsion Topical Lotion Topical Liquid Topical 7.5 % Shampoo Topical 1 % Solution Topical 0.5 % Liquid Topical 100 % Lotion Topical 5 % Gel Topical 10 % Shampoo Topical 2.5 % Shampoo Topical 2 g/100mL Lotion; shampoo Topical 1.4 % Shampoo Topical 1.4 % Shampoo Topical 0.57 g/114mL Shampoo Topical 3 % Shampoo Topical 1 g/100mL Shampoo Topical 1.02 mg/1mL Shampoo Topical 10.2 mg/1mL Shampoo Topical 2.5 mg/1mL Shampoo Topical 0.5 % w/w Shampoo Topical 25 mg/1mL Liquid Topical 1 % Liquid Topical 3 % Shampoo Topical 10 % Shampoo Topical 50 mg/1mL Shampoo Topical 5 g/100mL Emulsion Topical 30 % Liquid; shampoo Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at December 03, 2015 16:51 / Updated at October 11, 2024 18:19