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Displaying results 1931 - 1940 of 10000 in total
  1. Drug

    Estrane-3,17-dione

    go.drugbank.com/drugs/DB04693
    Experimental

    Estrane-3,17-dione is a potent inhibitor of isomerase.

  2. Drug

    5-methyltetrahydrofolic acid

    go.drugbank.com/drugs/DB04789
    InvestigationalNutraceutical

    5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. … It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases

    Synonyms: 5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid, N-MethyltetrahydrofolateInternational brands: Prefolic A
  3. Drug

    Inecalcitol

    go.drugbank.com/drugs/DB04796
    Investigational

    Categories: Vitamin D and Analogues
  4. Drug

    THIO-ATPA

    go.drugbank.com/drugs/DB04798
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    6-Hydroxy-5-undecyl-4,7-benzothiazoledione

    go.drugbank.com/drugs/DB04799
    Experimental

    Synonyms: 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole, 6-Hydroxy-5-undecyl-4,7-benzothiazoledioneCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Clioquinol

    go.drugbank.com/drugs/DB04815
    ApprovedVet approvedWithdrawn

    Clioquinol was withdrawn in 1983 due to neurotoxicity.

    Synonyms: 5-Chlor-7-jod-8-hydroxy-chinolin, 5-Chloro-7-iodo-8-quinolinolMixtures: BETNOVATE-C % 0,1 + % 3 KREM, 5 GR, BETNOVATE-C % 0,1 + % 3 MERHEM, 5 GR
  7. Drug

    Dantron

    go.drugbank.com/drugs/DB04816
    ApprovedWithdrawn

    Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity.

    International brands: Scatron DMixtures: Regulex D Cap
  8. Drug

    Zimelidine

    go.drugbank.com/drugs/DB04832
    ApprovedWithdrawn

    Zimelidine has been banned worldwide due to serious, sometimes fatal, cases of central and/or peripheral neuropathy known as Guillain-Barré syndrome and due to a peculiar hypersensitivity reaction involving

    Synonyms: (Z)-3-(4'-Bromophenyl)-3-(3''-pyridyl)dimethylallylamine, (Z)-zimelidineCategories: P-glycoprotein inhibitors, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  9. Drug

    Cyclandelate

    go.drugbank.com/drugs/DB04838
    ApprovedWithdrawn

    A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Roxadustat

    go.drugbank.com/drugs/DB04847
    ApprovedInvestigational

    Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. … It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring