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Nepicastat
go.drugbank.com/drugs/DB12979InvestigationalNepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder.
Categories: P-glycoprotein substratesMephedrone
go.drugbank.com/drugs/DB13108InvestigationalMephedrone has been investigated in Alcohol-Related Disorders and Amphetamine-Related Disorders.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesLusutrombopag
go.drugbank.com/drugs/DB13125ApprovedInvestigationalLusutrombopag is an orally bioavailable thrombopoietin receptor (TPOR) agonist developed by Shionogi & Company (Osaka, Japan). TPOR is a regulatory target site for endogenous thrombopoietin, which acts as a primary cytokine to promot...
Categories: P-glycoprotein substratesVon Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigationalThe human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the sit...
Mixtures: HAEMATE P, HAEMATE PEthyl chloride
go.drugbank.com/drugs/DB13259ApprovedWithdrawnEthyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. It was also used in other commerical applications as a chemical reagent. I...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesNaftopidil
go.drugbank.com/drugs/DB12092InvestigationalNaftopidil has been investigated for the treatment of Disorder of Urinary Stent.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesVinpocetine
go.drugbank.com/drugs/DB12131InvestigationalVinpocetine has been investigated for the treatment of Epilepsy.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBMS-275183
go.drugbank.com/drugs/DB12144InvestigationalBMS-275183 has been used in trials studying the treatment of Tumors and Non-small Cell Lung Cancer.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMK-0777
go.drugbank.com/drugs/DB12238InvestigationalMK-0777 has been used in trials studying the treatment of Schizophrenia, Anxiety Disorder, and Generalized Anxiety Disorder.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPolatuzumab vedotin
go.drugbank.com/drugs/DB12240ApprovedInvestigationalconsists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl
Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates