Ethyl chloride
Star0
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Summary
Ethyl chloride is a local anesthetic.
- Generic Name
- Ethyl chloride
- DrugBank Accession Number
- DB13259
- Background
Ethyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. It was also used in other commerical applications as a chemical reagent. It is still used in the treatment of cellulose to make ethylcellulose for commercial products. Ethyl chloride is used as a diagnostic tool to detect a dead tooth with nonviable pulp.
- Type
- Small Molecule
- Groups
- Approved, Experimental, Investigational
- Structure
- Weight
- Average: 64.514
Monoisotopic: 64.007977867 - Chemical Formula
- C2H5Cl
- Synonyms
- chloroethane
- Ethyl chloride
- monochloroethane
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Therapies
- Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAbemaciclib The risk or severity of methemoglobinemia can be increased when Abemaciclib is combined with Ethyl chloride. Abiraterone The risk or severity of methemoglobinemia can be increased when Abiraterone is combined with Ethyl chloride. Acetaminophen The risk or severity of methemoglobinemia can be increased when Acetaminophen is combined with Ethyl chloride. Acetazolamide The risk or severity of methemoglobinemia can be increased when Acetazolamide is combined with Ethyl chloride. Acetic acid The risk or severity of methemoglobinemia can be increased when Acetic acid is combined with Ethyl chloride. - Food Interactions
- No interactions found.
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Tuffner Clear Spray Ethyl chloride (12 %) + Benzoin resin (3 %) Aerosol Topical Mueller Sports Medicine, Inc. 1970-12-31 2003-08-01 Canada
Categories
- ATC Codes
- N01BX01 — Ethyl chloride
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as organochlorides. These are compounds containing a chemical bond between a carbon atom and a chlorine atom.
- Kingdom
- Organic compounds
- Super Class
- Organohalogen compounds
- Class
- Organochlorides
- Sub Class
- Not Available
- Direct Parent
- Organochlorides
- Alternative Parents
- Hydrocarbon derivatives / Alkyl chlorides
- Substituents
- Aliphatic acyclic compound / Alkyl chloride / Alkyl halide / Hydrocarbon derivative / Organochloride
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- chloroethanes (CHEBI:47554)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 46U771ERWK
- CAS number
- 75-00-3
- InChI Key
- HRYZWHHZPQKTII-UHFFFAOYSA-N
- InChI
- InChI=1S/C2H5Cl/c1-2-3/h2H2,1H3
- IUPAC Name
- chloroethane
- SMILES
- CCCl
References
- General References
- FDA Thailand Product Information: Ethyl chloride topical spray [Link]
- External Links
- KEGG Compound
- C18248
- PubChem Compound
- 6337
- PubChem Substance
- 347829290
- ChemSpider
- 6097
- 4141
- ChEBI
- 47554
- ChEMBL
- CHEMBL46058
- Wikipedia
- Chloroethane
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample dataNot Available Completed Treatment Acute Pain / Cutaneous Tumors / Head And Neck Cancer 1 somestatus stop reason just information to hide Not Available Completed Treatment Anesthesia therapy / Pain 1 somestatus stop reason just information to hide Not Available Completed Treatment Irreversible Pulpitis (Toothache) 1 somestatus stop reason just information to hide Not Available Completed Treatment Pain 1 somestatus stop reason just information to hide 4 Completed Prevention Pain 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Aerosol 100 ML Aerosol Topical Spray 100 ml/100ml - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 14.1 mg/mL ALOGPS logP 1.47 ALOGPS logP 1.19 Chemaxon logS -0.66 ALOGPS Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 0 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 16.06 m3·mol-1 Chemaxon Polarizability 6.42 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 119.255424 predictedDeepCCS 1.0 (2019) [M+H]+ 121.11089 predictedDeepCCS 1.0 (2019) [M+Na]+ 128.59593 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:38 / Updated at June 05, 2021 09:13