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Zavegepant
go.drugbank.com/drugs/DB15688ApprovedInvestigational[A258190,A258195] In March 2023, the FDA approved the use of zavegepant nasal spray for the acute treatment of migraine with or without aura in adults. … Zavegepant (BHV-3500) is a calcitonin gene-related peptide (CGRP) receptor antagonist.
Categories: Experimental Unapproved Treatments for COVID-19, Calcitonin Gene-Related Peptide Receptor AntagonistsUblituximab
go.drugbank.com/drugs/DB11850ApprovedInvestigational[A241045] In December 2022, ublituximab was approved by the US FDA for the treatment of relapsing forms of multiple sclerosis, becoming the first and only anti-CD20 monoclonal antibody for multiple sclerosis … allowing for administration in a one-hour infusion twice-a-year following the starting dose.
Fluocortolone
go.drugbank.com/drugs/DB08971ApprovedWithdrawnFluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders.
Categories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, Corticosteroids for Systemic Use, PlainEtripamil
go.drugbank.com/drugs/DB12605ApprovedInvestigational[A275243, A275248] The nasal formulation of etripamil was first approved by the FDA on December 12, 2025 for the conversion of acute symptomatic episodes of paroxysmal supraventricular tachycardia (PSVT
Imetelstat
go.drugbank.com/drugs/DB14909ApprovedInvestigational[A187838] Standard therapy for anemia in patients with MDS involves the use of erythropoiesis-stimulating agents (e.g. … [A187838] Imetelstat received FDA approval in June 2024 for use in certain patients with MDS who have transfusion-dependent anemia and are unable to use ESAs.[L50883,L50888]
Sulfanilamide
go.drugbank.com/drugs/DB00259ApprovedWithdrawnSulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseBrimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigational[A178969] The ophthalmic solution of brimonidine was first approved by the FDA in 1996 as Alphagan [label] and brimonidine is the only selective alpha-adrenergic receptor agonist approved for chronic treatment … [L6535] Brimonidine is the first topical treatment approved for facial erythema of rosacea.[A178978]
Categories: Adrenergic alpha-2 Receptor AgonistsConivaptan
go.drugbank.com/drugs/DB00872ApprovedIt was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). … Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).
Categories: Antidiuretic Hormone Receptor AntagonistsCholine C-11
go.drugbank.com/drugs/DB09563ApprovedCholine C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging of pat ients with suspected prostate cancer recurrence and non-informative bone scintigraphy, computerized
Remoxipride
go.drugbank.com/drugs/DB00409ApprovedWithdrawnRemoxipride is an atypical antipsychotic agent that is specific for dopamine D<sub>2</sub> receptors.
Categories: Dopamine D2 Receptor Antagonists