Sulfanilamide is a sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
- Mechanism
- Curator reviewed
Sulfanilamide is a competitive inhibitor of bacterial enzyme dihydropteroate synthetase. This enzyme normally uses para-aminobenzoic acid (PABA) for synthesizing the necessary folic acid. The inhibited reaction is normally necessary in these organisms for the synthesis of folic acid. Without it, bacteria cannot replicate.
- Primary indication
- For the treatment of vulvovaginitis caused by Candida albicans.Curator reviewed · 1 structured indication
- Formula / weight
- C6H8N2O2S · 172.205 g/mol (avg)
- First approval
- Canada, 1995 · United States, 1965
- Also known as
- p-aminobenzenesulfamide · p-aminobenzenesulfonamide · para-aminobenzenesulfonamide · Prontosil album · Streptocide
- Code names
- 1162 F · F-1162 · NSC-7618
Resolves to
FDDDEECHVMSUSB-UHFFFAOYSA-NSMILESNC1=CC=C(C=C1)S(N)(=O)=OWhat you can answer from here — as of September 23, 2026
Which drugs share a target with Sulfanilamide, and which of those have an active Phase 3 trial?
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