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Chlorphentermine
go.drugbank.com/drugs/DB01556ApprovedIllicitWithdrawnA sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension.
Synonyms: a,a-Dimethyl-p-chlorophenethylamineDoxercalciferol
go.drugbank.com/drugs/DB06410ApprovedInvestigationalD2. … Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin
Categories: Vitamin D and AnaloguesSynonyms: 1-Hydroxyvitamin D2, 1α-hydroxyvitamin D2Alizapride
go.drugbank.com/drugs/DB01425InvestigationalAlizapride is a dopamine antagonist that is capable of demonstrating both prokinetic and antiemetic effects. This kind of pharmacological activity makes it effective for use in the treatment of various kinds of nausea and vomiting, inclu...
Categories: Dopamine D2 Receptor AntagonistsZuranolone
go.drugbank.com/drugs/DB15490ApprovedInvestigationalUnlike other more common GABA<sub>A</sub> positive allosteric modulators on the market like benzodiazepines, zuranolone can modulate both synaptic and extrasynaptic GABA<sub>A</sub> conductance due to … [A260776,A260786] Zuranolone was designed with a pharmacological profile of a neuroactive steroid in mind while also possessing a pharmacokinetics profile of an oral, once-daily dosing formulation.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTribulus terrestris
go.drugbank.com/drugs/DB14358InvestigationalIt is not an approved drug.
Mixtures: Medi DP Energy BarDebrisoquine
go.drugbank.com/drugs/DB04840ApprovedAn adrenergic neuron-blocking drug similar in effects to guanethidine. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPralatrexate
go.drugbank.com/drugs/DB06813ApprovedInvestigationalPralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma [L37674]. … Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts.
Urea C-13
go.drugbank.com/drugs/DB09510ApprovedInvestigationalExhaled breath samples can then be collected and measured for the presence of radioactivity. … Both forms can be used within the Urea Breath Test, however some may prefer 13C as it is non-radioactive compared to 14C, which may be preferable in pregnant women and children.
Pentobarbital
go.drugbank.com/drugs/DB00312ApprovedVet approvedA short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally.
Mixtures: Cafergot Pb Tab, Cafergot Pb SupCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InducersBenralizumab
go.drugbank.com/drugs/DB12023ApprovedInvestigationalIt is an afucosylated IgG which gives it high affinity for the FcγRIIIα receptor in natural killer cells, macrophages and neutrophils.