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Bendazac
go.drugbank.com/drugs/DB13501ApprovedWithdrawna small handful of regions may continue to have the medication available for purchase and use either as a topical anti-inflammatory/analgesic cream or eye drop formulation. … Bendazac is an oxyacetic acid [A39863, A39869].
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingVerapamil
go.drugbank.com/drugs/DB00661ApprovedInvestigational[L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer, each of which is pharmacologically distinct - the S-enantiomer carries approximately 20-fold … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced
Mixtures: TARKA® SR TABLETAS, TARKA® SR240/4 TABLETAS.Categories: MATE 1 Inhibitors, MATE 2 InhibitorsAcetarsol
go.drugbank.com/drugs/DB13268ApprovedWithdrawnAcetarsol, with the molecular formula N-acetyl-4-hydroxy-m-arsanilic acid, is a pentavalent arsenical compound with antiprotozoal and antihelmintic properties. … [L2622] It was first discovered in 1921 by Ernest Fourneau at the Pasteur Institute. It was developed by Neolab Inc, and approved by Health Canada as an antifungal on December 31, 1964.
Streptomycin
go.drugbank.com/drugs/DB01082ApprovedInvestigationalVet approved[A233325,A232294] Although streptomycin was the first antibiotic determined to be effective against mycobacterium tuberculosis, it has fallen out of favor due to resistance and is now primarily used as … Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s.
Synonyms: 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranosideCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexPlazomicin
go.drugbank.com/drugs/DB12615ApprovedThe structure of plazomicin was established via appending hydroxylaminobutyric acid to [DB12604] at position 1 and 2-hydroxyethyl group at position 6' [A33942]. … It is marketed as Zemdri and is administered via once-daily intravenous infusion.
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsClofazimine
go.drugbank.com/drugs/DB00845ApprovedInvestigationalWithdrawnClofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as [dapsone], for the treatment of leprosy. … It was originally described in 1957 and was the prototypical riminophenazine dye - a bright-red dye that, in its clinical use, results in long-lasting discoloration of the skin and bodily fluids.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: CLOFZIMIN® 100 MGDL-alpha-Tocopherol
go.drugbank.com/drugs/DB14476ApprovedInvestigationalSynonyms: Vitamin E DL-alpha, (±)-α-tocopherolMixtures: Eden With Vitamins A, C, and E, Folica BENefazodone
go.drugbank.com/drugs/DB01149ApprovedWithdrawnDrug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with the incidence of severe liver damage was shown to be approximately 1 in 250,000 to … Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb.
Synonyms: 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-oneCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein inducersDifenoxin
go.drugbank.com/drugs/DB01501ApprovedIllicitDifenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. Difenoxin alone is a USA Schedule I controlled drug, as it may be habit forming. … Motofen(R) is a brand mixture which combines atropine sulfate and difenoxin hydrochloride. It is approved by the FDA to treat acute and chronic diarrhea.
Synonyms: 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acidCategories: Heterocyclic Compounds, 1-RingCarindacillin
go.drugbank.com/drugs/DB09319ApprovedWithdrawnCarindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of [carbenicillin] marketed by Pfizer as Geocillin. It is no longer marketed in the United States.
Synonyms: 6β-{2-[(2,3-dihydro-1H-inden-5-yloxy)carbonyl]-2-phenylacetamido}-2,2-dimethylpenam-3α-carboxylic acidCategories: Penicillin G, Heterocyclic Compounds, 2-Ring