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Lonafarnib
go.drugbank.com/drugs/DB06448ApprovedInvestigationalHutchinson-Gilford progeria syndrome (HGPS) is a rare autosomal dominant disorder estimated to affect approximately one in 20 million individuals resulting in adverse symptoms associated with premature ageing: skeletal dysplasia, joint c...
Categories: Cytochrome P-450 CYP1A2 Substrates, Cytochrome P-450 CYP2A6 SubstratesClomethiazole
go.drugbank.com/drugs/DB06470InvestigationalClomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. It is a drug which is structurally related t...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesDeramciclane
go.drugbank.com/drugs/DB06512InvestigationalDeramciclane (EGIS-3886) is used for the treatment of a number of anxiety disorders. Deramciclane differs from other anti anxiety medications in that it is not a benzodiazepine and so has a different structure and target. It antagonizes ...
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsAprotinin
go.drugbank.com/drugs/DB06692ApprovedInvestigationalWithdrawnAprotinin is a protein-based drug that is also known as bovine pancreatic trypsin inhibitor (BPTI). Since it demonstrates the capacity to slow fibrinolysis, it has been employed to reduce bleeding during complex surgery such as heart and...
Mixtures: BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI, BERIPLAST-P COMBI SET 3 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICILornoxicam
go.drugbank.com/drugs/DB06725ApprovedInvestigationalLornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesBufuralol
go.drugbank.com/drugs/DB06726ExperimentalBufuralol is a new, non-selective -adrenoceptor blocking agent.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSulfaphenazole
go.drugbank.com/drugs/DB06729ApprovedSulfaphenazole is a sulfonamide antibacterial.
Synonyms: 3-(p-aminobenzenesulfonamido)-2-phenylpyrazoleCategories: Cytochrome P-450 CYP2B6 Inhibitors, Cytochrome P-450 CYP2C8 Inhibitors9-aminocamptothecin
go.drugbank.com/drugs/DB12515InvestigationalAminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMizolastine
go.drugbank.com/drugs/DB12523ApprovedMizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers).
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors3,5-diiodothyropropionic acid
go.drugbank.com/drugs/DB12629InvestigationalDITPA has been investigated in Congestive Heart Failure.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates