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Sennosides
go.drugbank.com/drugs/DB11365ApprovedInvestigationalSennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and empty the large intestine before surgery. … The medication is taken by mouth or via the rectum[FDA Label]. It typically begins working in minutes when given by rectum and within twelve hours when given by mouth[FDA Label].
Salts: Sennosides A and BMixtures: Senna and Docusate Sodium, Senna and Docusate SodiumPenicillium glaucum
go.drugbank.com/drugs/DB14171ApprovedPenicillium glaucum allergenic extract is used in allergenic testing.
Synonyms: Molds, rusts and smuts, penicillium glaucum, Molds, rusts and smuts, penicillium glaucusMixtures: Molds - Mold Mix 4Reteplase
go.drugbank.com/drugs/DB00015ApprovedInvestigationalWithdrawnRetavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains the activity-related kringle-2 and serine protease domains of human tPA. … Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA.
Synonyms: Human t-PA (residues 1-3 and 176-527)Categories: Enzymes and Coenzymes, Blood and Blood Forming OrgansColestipol
go.drugbank.com/drugs/DB00375Approved[FDA Label, F4555, F4567, L6262] In particular, as colestipol's general mechanism of action ultimately results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia
Categories: Compounds used in a research, industrial, or household settingSynonyms: Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxiraneSarocladium strictum
go.drugbank.com/drugs/DB14168ApprovedSarocladium strictum allergenic extract is used in allergenic testing.
Synonyms: Molds, rusts and smuts, acremonium strictum, Molds, rusts and smuts, cephalosporium acremoniumProducts: Molds, Rusts and Smuts, Cephalosporium acremoniumObecabtagene autoleucel
go.drugbank.com/drugs/DB17362ApprovedInvestigationalObecabtagene autoleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with a fast off-rate binding profile for CD19. … [L52450] Obecabtagene autoleucel was also investigated in other hematological cancers and systemic lupus erythematosus.[A265045]
Categories: Antineoplastic cell and gene therapy, Antineoplastic and Immunomodulating AgentsSynonyms: SELF-INACTIVATING LENTIVIRAL VECTOR CONSISTING OF 5' FUSION BETWEEN THE CMV PROMOTER AND HIV LTR, WHERE THE CMV PROMOTER REPLACES THE U3 REGION., A CHIMERIC ANTIGEN RECEPTOR (CAR) CONSISTING OLinvoseltamab
go.drugbank.com/drugs/DB17447ApprovedInvestigationalThis mechanism results in the targeted release of cytokines such as IL-2, IL-6, and IFN-gamma, promoting the selective lysis of BCMA-expressing cells and offering a novel immunotherapeutic approach for … [L53348][L53353] Linvoseltamab is indicated for adult patients with RRMM who have previously received at least three classes of therapy: a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38
Synonyms: human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMACategories: Amino Acids, Peptides, and Proteins, Bispecific B Cell Maturation Antigen-directed CD3 T Cell EngagerZopapogene imadenovec
go.drugbank.com/drugs/DB24672ApprovedInvestigational[L54071] It is the first and only therapy approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults with RRP, receiving full FDA approval on August 15, 2025.[L54081] … Recurrent respiratory papillomatosis (RRP) is a rare, debilitating disease driven by chronic human papillomavirus (HPV) 6 or 11 infection and characterized by recurrent benign tumors in the respiratory
Synonyms: under control of a human cytomegalovirus (CMV) promoter and terminated with a 3' untranslated region and a simian virus 40 (SV40) polyadenylation signal, Replication-deficient gorilla adenovirus vector (strain GC46) encoding human papillomavirus (HPV) type 6 and type 11 antigens comprising 11 epitopes derived from regions of the E2, E4, E6, and E7 proteinsEurotium amstelodami
go.drugbank.com/drugs/DB15526ApprovedEurotium amstelodami allergenic extract is used in allergenic testing.
Synonyms: Molds, rusts and smuts, aspergillus amsterdamiAtacicept
go.drugbank.com/drugs/DB06399ApprovedInvestigationalfactor (BAFF) and A Proliferation Inducing Ligand (APRIL). … [L63797] Reducing BAFF- and APRIL-mediated signaling lowers production of galactose-deficient IgA1, an aberrant antibody whose deposition in the kidney drives IgA nephropathy.
Categories: Amino Acids, Peptides, and Proteins, Decreased B Lymphocyte ActivationSynonyms: Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein (Fc5)